Several authors in various papers attribute the toxic effects of nanomaterials to the release of ions from the main nanostructure (nanoparticles, nanorods, etc.). This is easy to perceive in the case of metal oxides and in the case of metals such as silver (1st Ionization energy of silver: 731.0 kJ·mol−1). About gold? Why gold nanoparticles induces toxic effects in living cells? It is possible that gold ions are released by gold nanoparticles (1st Ionization energy of gold: 890.1 kJ·mol−1)?