Hi i'm really bad at this kind of statistics so i hope someone can help me who has more understanding of how it works.
I have a genetic data sheet, and i want to calculate an odds ratio. N=48 of Control with 15 positive for a certain polymorfism (heterozygote) , N=88 of Patient group, and of this group 19 heterozygote and 2 homozygote. To be easy i simply combined hetero and homozygotes (21).
To get the odds ratio i did the following.
pc=positives for polymorfism (control group)
nc=negatives for polymorfism (control group)
pp=positives for polymorfism (patient group)
np=negatives for polymorfism (patient group)
But i got stuck on how to calculate the p-value, i need a high and a low value to know if the polymorfism is a significant change. First time i ever tried this. Though i know the solution (due to a filler spreadsheet) i want to know the mechanics.
The solution to this is
So any help on how to get to these values will be very appreciated.