Notices
Results 1 to 7 of 7
Like Tree2Likes
  • 1 Post By HeavenDragonslayer
  • 1 Post By Implicate Order

Thread: Hello there! So, how hard can the whole "neurophysiology"-thingy really be? :D

  1. #1 Hello there! So, how hard can the whole "neurophysiology"-thingy really be? :D 
    Forum Freshman
    Join Date
    Dec 2013
    Posts
    6
    Hey there everyone! I'm going to attempt keeping this short (I'm prone to writing essays when asked a simple yes or no question )

    The name's Patrik, I hail from Sweden where it currently hails.

    I've always had a curious mind, but it's of late that I've actually started to read up on the things that fascinates me. Primarily I'm intrigued by the way our minds work. Let me elaborate as to why.

    I'm throwing it out there right away; I've been suffering from major depressive disorder for as long as I can remember. I have gone through the motions, tried every SSRI on the market, cognitive behavioral therapy and the such. It was just last year that I managed to muster enough motivation to find a solution to the way my being worked, on my own, primarily through anger and frustration over how doctors and psychiatrists went about it.

    From the get-go, I've been plagued by a tremendous lethargy, I've had to sleep way more than the other kids, and this tiredness has held a firm grip over me, and still does, without failing. Add to this a pretty much absolute lack of motivation, will, creative drive/outlet, passion... It has been rough!

    I have always felt that my mind is working against me; Like a spunge, I suck in the tiniest observation of the most irrelevant piece of nothingness. These notions, these pieces of everything and nothing, I then try to fit together, to make coherent and contextual sense when viewed in relation to every single impression my mind has stored throughout life. This is not time spent well by my brain seeing as the world is not linear as such and the palette spans a spectrum of millions and millions of nuances that my mind entirely skip.

    This is a war of hundreds and hundred of thoughts running rampant at once, trying to make sense of the sensible and the senseless. The verbalisation of my can of coo-coo is just a fragment of that which apparently works subconsciously.

    I've had brief moments of "clarity" lasting from 2-3 hours to maximum of two days, a few times per year; I would draw really great pictures from my mind without having practiced holding a pencil prior. I would sit for hours and I was able to focus on what I was doing, oh man, those are the moments I remember most fondly. That is also why it's so horrible to know that I have the potential, but it's locked up deep inside of my mind, behind a veil, blurring and obscuring my potential and essentially removing my ability to focus and keep attention on something for more than a few seconds.

    So, as I was trying out Venlafaxine (an SNRI known also as Efexor) I grew weary of trying anti-depressant after anti-depressant without having any positive effect on my mood at all. It would cut the 'tops' but I would fall just as deep. This accentuated the 'lows' by the loss of 'tops' leading doctors to try new meds with about a years interval. As Venlafaxine proved to be just as worthless in countering the depression while slightly improving my ever-present mental and physical exhaustion, I started to read up on the working of these medications.

    This is where the fun began; first by the simple notion of me not settling for "taking pills, hoping for the best" as my mother have done her entire life and is content with - it meant that I have some sort of drive somewhere.

    I was truly fascinated by what I read about serotonin, dopamine, noradrenaline, melatonin, histamine... ionotropic receptors and metabotropic receptors... Agonistic binding, antagonistic binding.. What goes where and what causes this or that. Activity in different parts of the brain and the complexity of our reward system and how the autonomous nerve system is affected by this or that and the reponse in the somatic one... Good lord, I have no idea of what I'm reading and for every question I find the answer to, twenty new questions appear.

    So I came to a conclusion which I presented to my new doctor, that my depression did not stem from 5-HT2 prevalence/activity, rather a significant dopaminergic and noradrenergic disturbance that's not remedied by their insignificant increase in release that most SSRI's provide. It was really great to see him light up and skip the Donald Duck-explanation of things. I was even more confused by how he explained things using the terminology he used but I'm ever so thankful that he does use it. I learn so much more and I'm able to finally have a dialogue with a doctor who does not adhere to a simple list of hierarchal treatment regimen, set in stone as if every patient were the same.

    I have some hopes about my future now and that future is me smiling, singing to my hearts content with an ability to express myself with my creativity that I so fervously seek to find access to.

    That was a handful! If I managed to keep someone's interest through this rant about a guy and his depression, I thank you for reading!

    2013 has been the worst year of my life as well as the best year in my life. I've loved, I've sung, I've overcome addiction, I've learned, I've lost, I've laughed, I've cried...

    Here's a song about my year... This was one of the brief moments of clarity, where I managed to put my feelings into song... It may sound oh so cheezy and it may not appeal to anyone but me but if you've got a minute, feel free to lend an ear.

    /soundcloud.com/archdementh/no-more-of-this

    I look forward to read, learn, post and getting to know the people here

    /Patrik

    EDIT; Good job at keeping it short, sport xD


    Ascended likes this.
    Reply With Quote  
     

  2.  
     

  3. #2  
    Forum Masters Degree Implicate Order's Avatar
    Join Date
    Oct 2013
    Location
    27.4679 S, 153.0278 E
    Posts
    610
    Quote Originally Posted by HeavenDragonslayer View Post
    I look forward to read, learn, post and getting to know the people here
    Hi HeavenDragonslayer (I like your nick by the way)

    Great to have you on board. I was fascinated by your post and I am sure with your acquired knowledge of the mind, that your future contributions on this forum will be greatly appreciated. I too am particularly interested in the power of the mind (in both it's capacity to 'cripple' or to the other extreme 'enlighten' humanity)

    I hope those 'brief moments of clarity' come easier for you over time and maybe your quest for knowledge is actually directing you towards that powerful place. Your post above was incredibly interesting, cogent and well constructed by the way which reflects very positively on your mindset. Take care and I hope to hear much more from you :-))


    Ascended likes this.
    Quidquid latine dictum, altum videtur
    Reply With Quote  
     

  4. #3  
    Forum Radioactive Isotope cosmictraveler's Avatar
    Join Date
    May 2005
    Location
    Key West, Florida, Earth
    Posts
    4,788
    Welcome aboard.

    I too suffer from manic depression and bipolar disorder. I am taking Lithium, Wellbutrin and Seriquel. The Lithium is the best for the depression and it is a natural substance that my body seems to lack. I've been doing very well with this "mix" of medications. Just wondering if you ever took Lithium for your depression?
    When the power of love overcomes the love of power the world will know peace.
    Jimi Hendrix
    Reply With Quote  
     

  5. #4  
    Forum Freshman
    Join Date
    Dec 2013
    Posts
    6
    Quote Originally Posted by Implicate Order View Post
    Quote Originally Posted by HeavenDragonslayer View Post
    I look forward to read, learn, post and getting to know the people here
    Hi HeavenDragonslayer (I like your nick by the way)

    Great to have you on board. I was fascinated by your post and I am sure with your acquired knowledge of the mind, that your future contributions on this forum will be greatly appreciated. I too am particularly interested in the power of the mind (in both it's capacity to 'cripple' or to the other extreme 'enlighten' humanity)

    I hope those 'brief moments of clarity' come easier for you over time and maybe your quest for knowledge is actually directing you towards that powerful place. Your post above was incredibly interesting, cogent and well constructed by the way which reflects very positively on your mindset. Take care and I hope to hear much more from you :-))
    One's gotta keep the power metal banner up high! (though my actual middle name is Dragonslayer. I lost a drunk-dare a few years ago, and my word is bond xP)

    Glad to hear you managed to plow through! I, myself hope to someday be able to respond with the knowledge I've acquired and not just run around looking for answers. That might take a while though, considering this actually is 'rocket surgery'.

    I'm currently going through a very thorough neuropsychiatric evaluation since my doctor is quite convinced that I've got ADHD/ADD, and that my previous evaluations that yielded no such labling, were wrong. I've been fighting to get an in-depth evaluation so hopefully they don't write me off just because I don't put the square blocks in the triangular sockets.

    Thanks again for reading and being so welcoming

    Welcome aboard.

    I too suffer from manic depression and bipolar disorder. I am taking Lithium, Wellbutrin and Seriquel. The Lithium is the best for the depression and it is a natural substance that my body seems to lack. I've been doing very well with this "mix" of medications. Just wondering if you ever took Lithium for your depression?


    Oh, I see, glad the cocktail works. Gives me some more hope =)

    Before I got this doctor, I kinda 'self-medicated' by getting ahold of Voxra (Wellbutrin), phasing out my Venlafaxine by means of experimentation; I jumped from 300mg to 150mg to see if I got struck by any of the infamous discontinuation symptoms. I was not struck I then, tapered (can't get too reckless), over a month from 150mg to 50mg and then just stopped. I've read such horrible stories about Efexor withdrawal, but I was spared, although I suspect the panic anxiety, which I've never had in my life prior to heartbreak this summer, was held back by it - I've gotten them quite a lot during the last month but the could also have manifested due to external factors.

    My doctor, when I told him about this, prescribed Bupropion at 300mg a day, as well as Valdoxan (Agomelatine). I'm not comfortable with having more than one medication at a time, so I read up about it and it seems very promising due to it's very different mechanism of action. I don't know the word in English, but it's basically free from the exaggeration of the depression you get while starting with SSRI and SNRI, as well as no discontinuation issues/withdrawal at all.

    This is one reason I came to these boards actually; could it ever be possible that that which goes up, doesn't necessarily need to come down? I guess I believe in some sort of cosmic balance of things :P A medication providing benefits while not having any side-effects worth mentioning? Drugs targeting specific receptors or promoting cascade release of 'the good stuff' without down-regulation of these receptors? It's a thought I can not quite wrap my mind around; a substance, say, ten times more potent than meth-amphetamine, yet only leaves you at baseline when coming down. It doesn't fit well into the reality I've come to accept :3

    About lithium; my doctor mentioned it and how it could be worth trying. However, there is this one very prevalent side-effect that will keep me from ever trying it out; hair loss. I'm way too vain for my own good, but my hair is just not a compromise I'm willing to challenge If I may ask, did you your lion mane take a beating by the lithium?

    Cheers!
    Last edited by HeavenDragonslayer; December 11th, 2013 at 04:56 PM.
    Reply With Quote  
     

  6. #5  
    Ascended Member Ascended's Avatar
    Join Date
    Apr 2012
    Location
    Norfolk
    Posts
    3,418
    Hello HeavenDragonslayer, cool introduction. I just wanted to welcome you aboard
    Everything has its beauty, but not everyone sees it. - confucius
    Reply With Quote  
     

  7. #6  
    Forum Radioactive Isotope cosmictraveler's Avatar
    Join Date
    May 2005
    Location
    Key West, Florida, Earth
    Posts
    4,788
    About lithium; my doctor mentioned it and how it could be worth trying. However, there is this one very prevalent side-effect that will keep me from ever trying it out; hair loss. I'm way too vain for my own good, but my hair is just not a compromise I'm willing to challenge If I may ask, did you your lion mane take a beating by the lithium
    Not at all and I've been on it for over 10 years now. Do have blood work done to make sure my liver isn't being bothered though.
    When the power of love overcomes the love of power the world will know peace.
    Jimi Hendrix
    Reply With Quote  
     

  8. #7  
    Time Lord zinjanthropos's Avatar
    Join Date
    Dec 2005
    Location
    Driving in my car
    Posts
    5,378
    Hello there! So, how hard can the whole "neurophysiology"-thingy really be?
    Almost as hard as spelling neuropsychopharmacology.
    All that belongs to human understanding, in this deep ignorance and obscurity, is to be skeptical, or at least cautious; and not to admit of any hypothesis, whatsoever; much less, of any which is supported by no appearance of probability...Hume
    Reply With Quote  
     

Similar Threads

  1. Replies: 27
    Last Post: July 1st, 2013, 08:16 AM
  2. Replies: 6
    Last Post: May 9th, 2013, 08:45 AM
  3. "MOND", Prelude to "Critique of the Universe, Introduction"
    By Gary Anthony Kent in forum Astronomy & Cosmology
    Replies: 40
    Last Post: January 28th, 2012, 01:31 AM
  4. "Dating" posts split from "Purpose of life" thread
    By Christopher Ball in forum Pseudoscience
    Replies: 155
    Last Post: October 16th, 2011, 05:37 AM
  5. "Dating" posts split from "Purpose of life" thread
    By Christopher Ball in forum Earth Sciences
    Replies: 90
    Last Post: October 11th, 2011, 10:35 AM
Bookmarks
Bookmarks
Posting Permissions
  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •