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Thread: Inactivated Virus Efficacy question

  1. #1 Inactivated Virus Efficacy question 
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    Does inactivated virus in general has low efficacy compared to mRNA? The only thing i know as of now is that inactivated are the traditional method (proven therefore safer choice) while mRNA are much more recent technique (to be proven).

    PS: Double Helix, for the love of ur g0d, dont post here. This is not youtube.


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    Quote Originally Posted by xingha View Post
    Does inactivated virus in general has low efficacy compared to mRNA? The only thing i know as of now is that inactivated are the traditional method (proven therefore safer choice) while mRNA are much more recent technique (to be proven).

    PS: Double Helix, for the love of ur g0d, dont post here. This is not youtube.
    You are quite correct. This is not YouTube, which has a lot of nonsense on it. And I don't do nonsense, or videos.

    You are incorrect in making the assumption that I have a god of any kind. I worship science, usually the reproducible kind. Nothing else with suffice.

    If one posts nonsense on this site, one usually gets hammered by people who know better. It seems that you simply do not like the contents of some of my posts. Freedom of speech has that nasty problem of people writing and saying things you might not appreciate. But for scientists, and many others who believe in freedom, there is nothing more important than the truth. It should be the ultimate endeavor of all people. Sadly that is not always the case.

    But regarding your question : "Does inactivated virus in general has low efficacy compared to mRNA?"

    A quick google on Sinovac shows a link to a WHO website that indicates :

    "How efficacious is the vaccine? A large phase 3 trial in Brazil showed that two doses, administered at an interval of 14 days, had an efficacy of 51% against symptomatic SARS-CoV-2 infection, 100% against severe COVID-19, and 100% against hospitalization starting 14 days after receiving the second dose."

    end quote (dated June 2, 2021)

    Of course this is likely data from an earlier variant, and it is probable these numbers could fall against the delta variant.

    The mRNA efficacy looks a lot better, and probably relates to directing the immune system against the most significant protein on the virus, that of the spike protein and its receptor binding domain.

    The Sinovac vaccine, which uses the intact, inactivated virus, has the immune system targeting many areas of the virus unrelated to its ability to infect people, which likely is responsible for its reduced efficacy "against symptomatic SARS-CoV-2 infection". But since it appears to keep most people alive, it must be doing a good job.

    If you would like to challenge some of my claims in other threads, I would be happy to engage in debate regarding their contents and accuracy. But you may not be so interested in my responses.

    Peace and truth be with you, and yours.


    Last edited by Double Helix; August 26th, 2021 at 09:31 AM.
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