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Thread: Ebola Virus - What should you do?

  1. #301  
    Forum Masters Degree Tranquille's Avatar
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    For goodness sake.

    He told her where he was from. The hospital admitted the ball was dropped when she did not inform the doctors of where he was from. So please stop with the moronic conspiracies and no, you won't see the patient notes because patient notes are rarely displayed to the general public. You do not know what was said or asked or how it was asked, so don't invent it instead. And if you were able to add one and two together, it would be clear that his patient notes would not reveal anything since the nurse did not write up where he came from in his file. If he or she had written it up in his file, he would not have been sent home with anti-biotics because if it was in his file, the doctors would have seen it.
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    Quote Originally Posted by Tranquille View Post
    For goodness sake.

    He told her where he was from. The hospital admitted the ball was dropped when she did not inform the doctors of where he was from. So please stop with the moronic conspiracies and no, you won't see the patient notes because patient notes are rarely displayed to the general public. You do not know what was said or asked or how it was asked, so don't invent it instead. And if you were able to add one and two together, it would be clear that his patient notes would not reveal anything since the nurse did not write up where he came from in his file. If he or she had written it up in his file, he would not have been sent home with anti-biotics because if it was in his file, the doctors would have seen it.
    So somehow you can tell that there is no mention that Duncan "came from Liberia" on the original file! I reckon it will be there, just to be different.
    And I do know how to add 1+1 thank you very much, it is 3 isn't it?

    What doctor today prescribes antibiotics for a so called viral infection? I think they weren't that interested in the case as he didn't have medical insurance. Now that is cynical, isn't it?
    They need to be investigated IMO.
    Health regulators not rushing to probe Dallas hospital’s handling of Ebola patient | Dallas Morning News
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  3. #303  
    Universal Mind John Galt's Avatar
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    Quote Originally Posted by RobbityBob1
    Quote Originally Posted by John Galt
    This is isn't about you. (Although WMAP data may, superficially, suggest you are at the centre of the universe, this turns out to be a frame of reference situation.) This is considerably more important than about you winning or losing an argument.
    I had to think back to a possible story that elicited my post. I know it is not about me, but since the forum has agreed that the survivors could play a role in controlling the spread of Ebola I was going to try and spread the message, but at this stage all email addresses tried have not worked.
    Do you know an email address to someone within the UN? Could you share it via PM please if you do?
    1. (The emboldened phrase above) How can you possibly imagine that the authorities have not already considered the possible use of all resources in the affected countries? Do you seriously imagine that the hundreds of highly skilled and intelligent people have not considered such possibilities? Bob, the only way to describe your action in this matter is "stupid". Mind numbingly stupid. Why will you never think before you act?
    2. (the green phrase above) If it took a fraction of five minutes to find a raft of email addresses for UN officials, how come you could not do so?
    3. (underlined phrase) You asked me if I knew an email address to someone in the UN. You did not ask me if I knew someone in the UN. Once again your English comprehension lets you down badly. When are you going to do some work on this?
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  4. #304  
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    Quote Originally Posted by John Galt View Post
    Quote Originally Posted by RobbityBob1
    Quote Originally Posted by John Galt
    This is isn't about you. (Although WMAP data may, superficially, suggest you are at the centre of the universe, this turns out to be a frame of reference situation.) This is considerably more important than about you winning or losing an argument.
    I had to think back to a possible story that elicited my post. I know it is not about me, but since the forum has agreed that the survivors could play a role in controlling the spread of Ebola I was going to try and spread the message, but at this stage all email addresses tried have not worked.
    Do you know an email address to someone within the UN? Could you share it via PM please if you do?
    1. (The emboldened phrase above) How can you possibly imagine that the authorities have not already considered the possible use of all resources in the affected countries? Do you seriously imagine that the hundreds of highly skilled and intelligent people have not considered such possibilities? Bob, the only way to describe your action in this matter is "stupid". Mind numbingly stupid. Why will you never think before you act?
    2. (the green phrase above) If it took a fraction of five minutes to find a raft of email addresses for UN officials, how come you could not do so?
    3. (underlined phrase) You asked me if I knew an email address to someone in the UN. You did not ask me if I knew someone in the UN. Once again your English comprehension lets you down badly. When are you going to do some work on this?
    Did you read the post where you replied to my request? It was some sort of goading about that I "shouldn't try to outsmart" you. I do wonder what is wrong with you John. You seem to be nice but at the next moment you turn around and make me feel so trashed. I want you to get help, medical help possibly please.
    When you gave me that address you didn't say where it came from so I can make any guess I like. I thought you might have contacts in high places. Thanks for looking it up in google, and in the end I did find Helen clark's un email too, but I haven't actually tested it yet. I had already tried two addresses but both were invalid, so I was real pleased to have one that worked at last.
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  5. #305  
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    Now, back to the actual issue: this is the latest update from CDC, Atlanta.

    Outbreak Update


    • On 9/30/2014, CDC confirmed, the first travel-associated case of Ebola to be diagnosed in the United States.
    • New cases have been reported from Guinea, Liberia, and Sierra Leone. Nigeria and Senegal have not reported any new cases since September 5, 2014, and August 29, 2014, respectively. In Senegal, all contacts have now completed their 21-day follow up, with no further cases of Ebola reported.
    • On August 29, 2014, Senegal's Ministry of Public Health and Social Affairs announced a case of Ebola virus disease (EVD) in Senegal. The case is in a man from Guinea who traveled to Senegal.
    • The Democratic Republic of the Congo (DRC) has reported cases of Ebola. These cases are not related to the ongoing outbreak of Ebola in West Africa. For information on the outbreak in DRC, see the 2014 Ebola Outbreak in DRC page.
    • HHS has contracted with Mapp Biopharmaceutical Inc. to develop and manufacture ZMapp. Mapp Biopharmaceutical will manufacture a small amount of the drug for early stage clinical safety studies and nonclinical studies.
    • NIH will begin initial human testing of an investigational vaccine to prevent EVD in early September and is working with a company to develop an antiviral drug to treat Ebola.
    • U.S. Department of Defense has funded two companies that are developing drug therapies for Ebola and is working with another company to develop an Ebola vaccine.
    • CDC returned a staff member from West Africa by charter flight after the employee had low-risk contact with an international health worker who recently tested positive for Ebola. The CDC staff member was not sick with Ebola, did not show symptoms of the disease, and therefore posed no risk to friends, family, co-workers, or the public


    For more information here is the CDC link.
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  6. #306  
    Forum Masters Degree Tranquille's Avatar
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    Quote Originally Posted by Robittybob1 View Post
    So somehow you can tell that there is no mention that Duncan "came from Liberia" on the original file! I reckon it will be there, just to be different.
    And I do know how to add 1+1 thank you very much, it is 3 isn't it?

    What doctor today prescribes antibiotics for a so called viral infection? I think they weren't that interested in the case as he didn't have medical insurance. Now that is cynical, isn't it?
    They need to be investigated IMO.
    Health regulators not rushing to probe Dallas hospital’s handling of Ebola patient | Dallas Morning News
    If it had been on his treatment file and what is accessed by the doctors, if the nurse who first spoke to him had put it in his paperwork, he probably would not have been sent home. Here is what the hospital has admitted:

    Even though a sick patient later diagnosed with Ebola told an emergency room nurse at a Texas hospital that he had recently traveled from West Africa, the nurse failed to pass on that information to other hospital staff, and that man was released from the hospital with antibiotics, officials said today.
    The first Ebola patient diagnosed in the U.S. was initially sent home after seeking care at Texas Health Presbyterian Hospital for symptoms consistent with the virus on Sept. 26, according to the U.S. Centers for Disease Control and Prevention.


    * * * * *



    In a news conference earlier today, Dr. Mark Lester, the executive vice president of the hospital, said the patient did not fully communicate his status to hospital staff and his overall clinical presentation was not typical at the time for Ebola.
    But he also said: "He volunteered that he traveled from Africa in response to a nurse operating the checklist and asking him the question. The clinicians did not factor that in. It was not part of their decision."
    He added that a nurse who saw the patient did ask him if he had traveled to Africa and he said yes. She did not communicate with the rest of the team. He did not offer an explanation.

    And here:

    During Governor Rick Perry's news conference a doctor from the Texas hospital revealed that the patient diagnosed with Ebola did disclose that he had traveled to Liberia but in the confusion of the ER this information did not get communicated to the doctors, or other health care officials who released the patient.
    Do they need to be investigated? Yes. As I noted earlier, they should also be investigated for why they then quarantined the man's relatives/friends in the apartment where he had been so ill with all of his contaminated bedding, bathroom, towels, clothes for days before they sent in professionals to clean it.

    But that does not mean you get to write a script for what was said by whom and then to carry on as if the nurse did not know about Ebola in Liberia because she's never been to Africa as though it's a big conspiracy. In other words, the case is bad enough, you don't need to invent a script to suit what you want it to be.
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    @ Tranquille - The whole situation is a shambles. I just hope they get it back under control quickly now.
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  8. #308  
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    Hmm... Found this unpleasant little tidbit; A professor in U.S. is telling Liberians that the Defense Department ‘manufactured’ Ebola - The Washington Post
    Apparently random idiots being allowed to spew can lead to fatal tragedy.
    I was some of the mud that got to sit up and look around.
    Lucky me. Lucky mud.
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    If you aren't already depressed!
    How Ebola sped out of control | The Washington Post
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    Is it true Duncan has died? The next question is how many more is he going to take with him? So far so good!
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  11. #311  
    Forum Masters Degree Tranquille's Avatar
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    Quote Originally Posted by Robittybob1 View Post
    Is it true Duncan has died? The next question is how many more is he going to take with him? So far so good!
    So far so good?

    What?

    Umm are you happy you think he died?

    Sorry to burst your bubble, but it appears as though he is still alive and apparently fighting for his life. So you'll have to leave off the celebrations for later.
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    Quote Originally Posted by Tranquille View Post
    Quote Originally Posted by Robittybob1 View Post
    Is it true Duncan has died? The next question is how many more is he going to take with him? So far so good!
    So far so good?

    What?

    Umm are you happy you think he died?

    Sorry to burst your bubble, but it appears as though he is still alive and apparently fighting for his life. So you'll have to leave off the celebrations for later.
    So far none of the contacts have developed symptoms. So far so good.
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  13. #313  
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    Ah okay.

    In that case, yes, so far so good.
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    Quote Originally Posted by Tranquille View Post
    Ah okay.

    In that case, yes, so far so good.
    But I must confess I am annoyed at Duncan, so I am not very sympathetic toward him, sorry.
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  15. #315  
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    According to the morning news, he took a turn for the worse over the weekend, but is still alive.
    Fixin' shit that ain't broke.
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    Quote Originally Posted by MacGyver1968 View Post
    According to the morning news, he took a turn for the worse over the weekend, but is still alive.
    And he is also getting a new drug to help him overcome the virus. brincidofovir
    Quote Originally Posted by Wikipedia
    Brincidofovir (CMX001) is an experimental antiviral drug being developed byChimerix for the treatment of cytomegalovirus. It also has activity againstadenoviruses, BK virus and herpes simplex viruses,[1][2] and preliminary tests have also shown it to have potential for the treatment of Ebola virus disease.[3]Brincidofovir is a prodrug of cidofovir.[2]
    The drug acts
    Mechanism of action[edit]

    Its active metabolite, cidofovir diphosphate, inhibits viral replication by selectively inhibiting viral DNA polymerases.[2] It also inhibits human polymerases but this action is 8-600 times weaker than its actions on viral DNA polymerases.[2] It also incorporates itself into viral DNA hence inhibiting viral DNA synthesis during reproduction.[2]
    It possesses in vitro activity against the following viruses:[19]

    You'd wonder why they are using it on a RNA virus when it action is against DNA polymerases? Ebola is an RNA virus.
    Quote Originally Posted by Wikipedia
    Replication[edit]

    Being acellular, viruses such as Ebola do not replicate through any type of cell division; rather, they use a combination of host- and virally encoded enzymes, alongside host cell structures, to produce multiple copies of themselves. These then self-assemble into viral macromolecular structures in the host cell.[8][better source needed] The virus completes a set of steps when infecting each individual cell:[citation needed]
    The virus begins its attack by attaching to host receptors through the glycoprotein (GP) surface peplomer and is endocytosedinto macropinosomes in the host cell.[18][non-primary source needed] To penetrate the cell, the viral membrane fuses with vesiclemembrane, and the nucleocapsid is released into the cytoplasm. Encapsidated, negative-sense genomic ssRNA is used as a template for the synthesis (3'-5') of polyadenylated, monocistronic mRNAs and, using the host cell's ribosomes, tRNA molecules, etc., the mRNA is translated into individual viral proteins.
    These viral proteins are processed, a glycoprotein precursor (GP0) is cleaved to GP1 and GP2, which are then heavily glycosylated using cellular enzymes and substrates. These two molecules assemble, first into heterodimers, and then into trimers to give the surface peplomers. Secreted glycoprotein (sGP) precursor is cleaved to sGP and delta peptide, both of which are released from the cell.[citation needed] As viral protein levels rise, a switch occurs from translation to replication. Using the negative-sense genomic RNA as a template, a complementary +ssRNA is synthesized; this is then used as a template for the synthesis of new genomic (-)ssRNA, which is rapidly encapsidated.
    The newly formed nucleocapsids and envelope proteins associate at the host cell's plasma membrane; budding occurs destroying the cell.
    Will it really help?
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    Dallas County prosecutor considering criminal charges against Ebola patient in Texas

    Dallas County prosecutor considering criminal charges against Ebola patient in Texas - The Washington Post
    Maybe we will get to see what was written on the admission form sometime soon.
    “We are looking at whether he intentionally and knowingly exposed the public to the virus,” said Debbie Denmon, a spokesperson for the Dallas County prosecutor’s office.

    “It’s the issue of holding someone accountable, that you can’t just get on an airplane and lie on a travel document and get to the United States and lie on a hospital document,” she said.
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    Eric Thomas Duncan died.
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  19. #319  
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    Quote Originally Posted by Robittybob1 View Post
    Eric Thomas Duncan died.
    There will be a lot of disappointed prosecutors.

    On the plus side, the myth that "just go to the US if you are exposed and they will save you" just took a big hit.
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  20. #320  
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    Quote Originally Posted by billvon View Post
    Quote Originally Posted by Robittybob1 View Post
    Eric Thomas Duncan died.
    There will be a lot of disappointed prosecutors.

    On the plus side, the myth that "just go to the US if you are exposed and they will save you" just took a big hit.
    How the botch-up occurred will need to be investigated. Then measures put in place hopefully to reinforce the proper procedures.

    You won't get around people lying or telling only half the truth so any procedure won't be foolproof.
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    Another day and no new patients in the USA. That is rather amazing. I wonder why they don't use the new drugs prophylactically? It could be cheaper in the long run. Maybe the risk of side effects is greater than the disease.
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  22. #322  
    Universal Mind John Galt's Avatar
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    This post is intended mainly to move Bob's "contribution" away from being the last and most visible item. But it is informative too.

    The October 8th update from CDC Atlanta:

    Outbreak Update

    • A confirmed case of Ebola has been reported in Spain.
    • On September 30, 2014, CDC confirmed, the first travel-associated case of Ebola to be diagnosed in the United States.
    • New cases have been reported from Guinea, Liberia, and Sierra Leone. Nigeria and Senegal have not reported any new cases since September 5, 2014, and August 29, 2014, respectively. In Senegal and Nigeria, all contacts have now completed their 21-day follow up, with no further cases of Ebola reported.
    • On August 29, 2014, Senegal's Ministry of Public Health and Social Affairs announced a case of Ebola virus disease (EVD) in Senegal. The case is in a man from Guinea who traveled to Senegal.
    • The Democratic Republic of the Congo (DRC) has reported cases of Ebola. These cases are not related to the ongoing outbreak of Ebola in West Africa. For information on the outbreak in DRC, see the 2014 Ebola Outbreak in DRC page.
    • HHS has contracted with Mapp Biopharmaceutical Inc. to develop and manufacture ZMapp. Mapp Biopharmaceutical will manufacture a small amount of the drug for early stage clinical safety studies and nonclinical studies.
    • NIH began initial human testing of an investigational vaccine to prevent EVD in early September and is working with a company to develop an antiviral drug to treat Ebola.
    • U.S. Department of Defense has funded two companies that are developing drug therapies for Ebola and is working with another company to develop an Ebola vaccine.
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  23. #323  
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    The WHO have reported that the number of deaths have now surpassed 4,000.

    Liberia has seen the worst out of that, with over half of the deaths coming from that country alone.

    Chris Dye from the WHO said the international response was helping, and the important thing now was to look forward.


    "We've asked for a response of about $1bn (£618m); so far we have around $300m (£185m) with more being pledged, so a bit less than half of what we need but it's climbing quickly all the time," he said.


    In April, the medical charity Medecins Sans Frontieres (MSF) warned of the potential spread of the virus, but at the time the WHO played down the claims, saying that Ebola was neither an epidemic, nor was it unprecedented.


    On Friday MSF reported a sharp increase of Ebola cases in the Guinean capital, Conakry, dashing hopes that the disease was being stabilised there.


    Meanwhile in Mali, an experimental serum is being tested on volunteer health workers.


    The trial spans several countries, and the results will be sent to experts to determine whether it can protect against Ebola.


    In other developments:

    • The Ebola crisis has resulted in the activation for the first time of the International Charter on Space and Major Disasters. Its normal role is to provide satellite imagery to make damage and hazard-assessment maps
    • Liberia's senate elections due next week have been postponed to help reduce the risk of voters spreading the virus
    • Nigeria's military has confirmed that more than 1,300 Nigerian peacekeeping troops have been quarantined in Liberia after coming into contact with a Sudanese man who later died of the disease. It had earlier denied such reports
    • Passengers at some British airports will be screened for Ebola
    • The US begins its programme of enhanced screening this weekend at five of its major airports, including JFK
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