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Thread: Marijuana & your medical opinion

  1. #1 Marijuana & your medical opinion 
    Forum Bachelors Degree GoldenRatio's Avatar
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    Just thought I would see what everyone's thoughts and opinions are regarding marijuana & its use in the medical community. If you belive it is benificial or not.

    Note: In no way wanting a debate or thread on the political, legal or social aspects attached to marijuana. Simply the medical ones


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    The sooner the legal impediments are removed, the sooner we'll be able to test the claimed medical benefits dispassionately.

    It sort of makes sense that it has an effect on the nausea suffered by chemotherapy patients given the well-known mmmmm, munchies! effects on healthy people. But it would be much better if researchers were free to work with different formulations and methods of delivery and well-founded estimations of who is most likely to benefit rather than oncologists looking over their shoulder as they whisper recommendations to their patients to try a joint and see if it helps with their nausea.

    Same thing goes for the benefits some people claim for cerebral palsy and other spasm / weakness / pain conditions. The only ones I know of are using smoothies of whole leaves. It would be a great improvement if research could be openly conducted with large numbers of volunteers to measure benefits and negatives for various kinds of patients and illnesses and properly calibrated doses in controlled conditions.


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    yes it can have medical uses but then again there are legal drugs which can also help with nausea pain etc. i don't think this drug is necessary medically.

    good recreational drug though
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  5. #4  
    Forum Professor jrmonroe's Avatar
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    I have worked in the pharmaceutical industry, and I think the context of "medicinal marijuana" as a pharmaceutical is a travesty (except, perhaps, to increase the appetite of some patients). Just admit to what people will use it as — a recreational substance similar to beer, wine or spirits.

    If they really want to go the professional pharmaceutical route, then all the testing needed to be performed would probably make it somewhat expensive to dispense as a joint. I don't see how they could assure quality control. They would need to have tests for concentration of the API, purity, kinds of non-active ingredients, research showing that non-active ingredients produce no adverse effects, etc. Are producers of medicinal marijuana actually applying to the FDA for approval through NDAs (New Drug Applications)? Apparently not, as it normally takes 10 to 15 years, and the FDA would probably not see any need to fast-track it.

    Apparently a "medicine" administered as a street drug. Where is the extraction of marijuana's API (active pharmaceutical ingredient) and its formulation as a tablet, capsule, liquid, patch, lollipop, etc? Smoking pot for medicinal purposes is like taking an opiate for moderate to severe pain, but for some odd reason, you need to cook it and main line it. I've never heard of such a thing as smoking a medicine. How then should it be administered to children?

    Is it / will it be / "dispensed" according to the actual amount of its API, or simply by grams? How does a practitioner determine the dosage for any given condition?

    What's the Latin prescription verbiage for "smoke" (v.), as in "Smoke one 1- to 2-gram spliff of sinsemilla-strength marijuana one hour before bedtime"? Probably "Fumus".

    Are "man boobs" and "the munchies" and "lung cancer" listed as possible side effects? Are any side effects listed? Who determined the side effects? Are "patients" warned not to drive or to operate heavy machinery?

    Will health insurance cover it? Are the non-smokers helping to pay for the smokers?

    Do the feds continue to list marijuana as an hallucinogen, as they have for many years? I would guess so.

    "Medicinal" marijuana is a mockery of professional medicine.
    Last edited by jrmonroe; January 31st, 2014 at 05:53 AM.
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    "Medicinal" marijuana is a mockery of professional medicine.
    It's still in the folk medicine - herbal plant category.

    Which is why none of the issues you raise about purity, dosage, delivery methods can be resolved until large population trials can be run to determine if all, some, any or none of the claimed benefits can be identified and measured. And that can't be done while the threat of prosecution hangs over the head of the trial subjects and/or the researchers themselves and/or the institutions proposing. financing or accommodating the research projects.
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    Quote Originally Posted by adelady View Post
    "Medicinal" marijuana is a mockery of professional medicine.
    It's still in the folk medicine - herbal plant category.
    homeopathy is bullshit
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    homeopathy is bullshit
    Yes it is. Homeopathy is just water (or sugar).

    But it's an entirely different thing from folk remedies and herbal preparations. Lots of drugs in common use are pure versions of herb based "medicines". The classic case being aspirin. We now have pure salicylic acid produced in exact dosages for specific purposes - and the range of purposes keeps on expanding.

    And this is the family of preparations that marijuana belongs in. Some plant distillations and other preparations have turned out to have no or little value. But some have definite, specific uses for particular conditions when provided in properly calibrated doses.

    Without research on the benefits claimed for marijuana, we can't determine how much, if any, benefit it offers to which kinds of patients in which circumstances and which doses. At the moment, it's a bit too much like chewing willow bark when you have a toothache instead of taking an aspirin tablet.
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    Quote Originally Posted by adelady View Post
    homeopathy is bullshit
    Yes it is. Homeopathy is just water (or sugar).
    are you ok mate?
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    Life-Size Nanoputian Flick Montana's Avatar
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    I agree with adelady. Not enough serious research has taken place. However, I have no problem with medical or recreational use of the substance so long as it is responsibly used.

    If someone has terminal cancer and marijuana is what makes them feel better, who am I to say they should go with a $100 a pill Big Pharm drug instead? Give them whatever works for them.
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    Quote Originally Posted by adelady

    Without research on the benefits claimed for marijuana, we can't determine how much, if any, benefit it offers to which kinds of patients in which circumstances and which doses.
    there has been plenty of research on Marijuana. google marijuana research. Labs on universities have conducted plenty of studies
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    there has been plenty of research on Marijuana. google marijuana research. Labs on universities have conducted plenty of studies
    Nothing like the multi-location, large scale population studies that are needed to work these things out. Seeing as the illegality of marijuana is a global issue, how can you conduct the multi-national studies that are usually done for these things? Several countries would consider imposing the death penalty for "trafficking" in marijuana for the quantities a researcher would need for a sizable project wth several hundred participants.
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  13. #12  
    Forum Bachelors Degree GoldenRatio's Avatar
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    I personally am in favor of it. I agree more research needs to be completed, Research that is impossible to do under current laws. However, used as a medicine or as a recreational activity. I see it having far less negative side effects & health consequences than current medication prescribed or legal stimulants like alcohol or tobacco.

    Quote Originally Posted by jrmonroe View Post
    If they really want to go the professional pharmaceutical route, then all the testing needed to be performed would probably make it somewhat expensive to dispense as a joint. I don't see how they could assure quality control. They would need to have tests for concentration of the API, purity, kinds of non-active ingredients, research showing that non-active ingredients produce no adverse effects, etc. Are producers of medicinal marijuana actually applying to the FDA for approval through NDAs (New Drug Applications)? Apparently not, as it normally takes 10 to 15 years, and the FDA would probably not see any need to fast-track it.
    I disagree. It could be sold as a herbal supplement just like any other herbal supplement. St johns wort for example is well known as being a mild anti-depressant. However, this is not regulated by the FDA nor are claims of being an anti-depressant supported by the FDA. I also do not see the price increasing, if anything it will drop severely. Consider beer & wine. Its perfectly legal to make your own in your home, yet for the price of all the supplies you are not saving any money and just better off buying it. Same with say tomatoes, your welcome to grow your own in your backyard. However at a dollar each, your not really coming out that far ahead. Marijuana is no harder to grow than tomatoes if you have the ability to grow one you can grow the other. Thus $100+ for an ounce would easily fall to maybe 5-10. Simply because no-one would pay $100 if they can grow it in their backyard legally.

    Quote Originally Posted by jrmonroe View Post
    Apparently a "medicine" administered as a street drug. Where is the extraction of marijuana's API (active pharmaceutical ingredient) and its formulation as a tablet, capsule, liquid, patch, lollipop, etc? Smoking pot for medicinal purposes is like taking an opiate for moderate to severe pain, but for some odd reason, you need to cook it and main line it. I've never heard of such a thing as smoking a medicine. How then should it be administered to children?

    Is it / will it be / "dispensed" according to the actual amount of its API, or simply by grams? How does a practitioner determine the dosage for any given condition?

    What's the Latin prescription verbiage for "smoke" (v.), as in "Smoke one 1- to 2-gram spliff of sinsemilla-strength marijuana one hour before bedtime"? Probably "Fumus".
    I do agree It would be hard to regulate how much someone should take to achieve relief from their symptoms. For 1 person, 1 gram might be a enough, someone else might need 2 or more. However, from what I have seen of being no overdose risk. I do not see how much someone takes being a factor.

    Also, opiates are prescribed for moderate to severe pain. Its actually one of the first drugs given (assuming no alergic reaction). It is also "main lined" quite often in hospital settings in the form of morphine. I also do not see how method of delivery mattering. I cannot think of any current medicine smoked for relief of medical conditions (aside from marijuana) however we have MANY inhaled medications. asthma medication, cold & sinus medication, even oxygen for people with poor gas exchange.

    Assuming problems are found, such as lung cancer. Im sure a smoked form will not be prescribed however there are many methods for getting drugs into the body.

    Quote Originally Posted by jrmonroe View Post
    Are "man boobs" and "the munchies" and "lung cancer" listed as possible side effects? Are any side effects listed? Who determined the side effects? Are "patients" warned not to drive or to operate heavy machinery?
    Agreed, side effects should be noted and mentioned by doctors. Agreed on not driving while intoxicated, same with any pain meds or muscle relaxants or several other medications.


    Quote Originally Posted by jrmonroe View Post
    "Medicinal" marijuana is a mockery of professional medicine.
    Disagree.
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