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Thread: Stem cells questions

  1. #1 Stem cells questions 
    Forum Sophomore Hymenophyllum's Avatar
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    From which part of body scientists take stem cells? Is the number of stem cells in the body constant? When it's changing?
    What is the difference between embryonic stem cells and "normal" ones?


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  3. #2  
    Life-Size Nanoputian Flick Montana's Avatar
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    Sounds like you have a lot of questions. I would recommend reading up: Stem Cell Basics [Stem Cell Information]


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    Forum Masters Degree Implicate Order's Avatar
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    Excellent article Flick. It truly is a fascinating area both for explaining the role of epigenetics in cellular differentiation, to understanding how medical breakthroughs using the pluripotency of stem cells could be a major windfall in addressing 'age old' problematic conditions, to providing an evo-devo context to examine our evolutionary record.

    To understand how a code combined with cellular chemistry is responsible for cellular differention from a pluripotent state to a specialised state leading to ultimate phenotypic structure and specialised function is a mind blower. To also observe a sweeping record of evolution of complexity through Ontongeny is another paradigm shift that answers so many questions. :-))

    PS in response to your question Hymenophyllum, the difference I think is related to their degree of pluripotency. As cells lose their pluripotency through specialisation, the forms that then can then specialise into are more restricted. Adult stem cells are more restricted in the forms they can take versus embryonic stem cells. The generic nature is lost to a degree through specialisation.

    You might be aware of experiments in mice with snapped spinal chords where pluripotent stem cells were injected into theese broken areas and they quickly developed into approriate specxialised cells to mend the break. That was problem 1 achieved....now how to fix the circuirty for problem 2 to fully recover the mice... which was throught to be a dillema. Enter the brain of the mice after removing a common enzyme that regulates neuronal cell growth, which then allowed the brain to re-configure the circuity to restore normal condition. Not only is the environmental chemistry important but the entire systemic context of the organism........*enters mind blown state again, and again, and again.......life is truly amazing.
    Last edited by Implicate Order; January 5th, 2014 at 09:16 PM.
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    Time Lord
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    Good link Flick.

    It didn't mention umbilical cord (and placental) blood stem cells. Few people have an ethical problem there since we used to just trash it.

    Hymenophyllum, depending on the country a baby born in hospital now may have its own cord blood "banked". Those personal stem cells are like a genetic reset in case of problems 20, 60, 100 years later in life. I urge all expectant parents to consider this.
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    Forum Sophomore Hymenophyllum's Avatar
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    THanks guys
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