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Thread: Melatonin

  1. #1 Melatonin 
    Forum Ph.D. stander-j's Avatar
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    So, I bought some Melatonin and B Vitamins the other day. Melatonin to get myself back on a regular sleep pattern. B Vitamins because, well, if I'm going to take CR hormone, I might as well have some crazy dreams while I'm at it. I've used melatonin in the past, and something that I'm starting to notice is that even though I feel like I've had a much better rest when I get up in the morning, I wake up several times a night. Every two hours or so. It's only for a minute or two each time, but this only happens when I use melatonin.

    Has anyone else ever experienced this with Melatonin? Does anyone have an idea what might be the cause of this? I was thinking... When you take supplemental Melatonin you are essentially boosting your sleep cycle and its intensity right? Is it possible that because of this, you are more sensitive to the peaks and valleys of the sleep cycle?


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    melatonin is 'made' in the pineal gland, if your body is not producing enough it's okay to take melatonin. this can be due to old age or what ever. if you take it as a supplement it can aid in REM sleep.

    you should also note that melatonin can have side effects.


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    Brassica oleracea Strange's Avatar
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    Sounds like melatonin can have all sorts of mildly unpleasant side effects:
    Melatonin side effects: What are the risks? - MayoClinic.com
    Melatonin for Sleep: Hormone and Supplement Effects on Sleep

    I used to work with people who took melatonin to avoid jet lag. It didn't seem to do much good. If anything they seemed to suffer far more jet lag than me (but maybe that is the reason they were taking the melatonin!)
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    Quote Originally Posted by Strange View Post
    Sounds like melatonin can have all sorts of mildly unpleasant side effects:
    Melatonin side effects: What are the risks? - MayoClinic.com
    Melatonin for Sleep: Hormone and Supplement Effects on Sleep

    I used to work with people who took melatonin to avoid jet lag. It didn't seem to do much good. If anything they seemed to suffer far more jet lag than me (but maybe that is the reason they were taking the melatonin!)
    firstly there are still clinical trials going on to understand the side effects of the drug. so you can't say for certain that it has bad side effects. secondly every drug has a different response depending on the person. just because you know a few people that the drug didn't respond well to doesn't mean it won't help the op
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    Brassica oleracea Strange's Avatar
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    Quote Originally Posted by bio View Post
    so you can't say for certain that it has bad side effects.
    Good job I didn't say that then.

    just because you know a few people that the drug didn't respond well to doesn't mean it won't help the op
    Good job I didn't say that then.

    I was actually surprised that there is some evidence it can help people (maybe I should have prefaced my anecdote with that?)
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    Forum Ph.D. stander-j's Avatar
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    Quote Originally Posted by bio View Post
    Quote Originally Posted by Strange View Post
    Sounds like melatonin can have all sorts of mildly unpleasant side effects:
    Melatonin side effects: What are the risks? - MayoClinic.com
    Melatonin for Sleep: Hormone and Supplement Effects on Sleep

    I used to work with people who took melatonin to avoid jet lag. It didn't seem to do much good. If anything they seemed to suffer far more jet lag than me (but maybe that is the reason they were taking the melatonin!)
    firstly there are still clinical trials going on to understand the side effects of the drug. so you can't say for certain that it has bad side effects. secondly every drug has a different response depending on the person. just because you know a few people that the drug didn't respond well to doesn't mean it won't help the op
    Some side effects are subjective, good to some and bad to others... But supplemental Melatonin definitely has objectively bad side effects too. Anecdotal or not, a quick search through forums will show numerous reports of people experiencing morning grogginess when they take melatonin. Remember, melatonin does influence your sleep phases, and waking up during the wrong sleep phase in the cycle will produce grogginess. That's why you might wake up feeling more tired than you originally were if you take a couple hour nap.

    Anyway, I've been using melatonin on and off as a sleep aid for years... All I'm really looking for in this thread is if anyone knows about any research explaining why some experience clockwork awakening throughout the night. I did some sleuthing myself, but all I can find are anecdotes similar to my own - people waking up every hour, two hours, some only once or twice... I'm just interested in the why.
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    Another relatively safe sleep aid is Benedryl. I generally prefer to use none of these and just sleep naturally, however sometimes you need to sleep "now" because you will have to be awake later... I find that 50mg of benedryl does the trick.
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    I've noticed the same thing. A suggested offering:

    The brain steps up production of Melatonin when readying for sleep and reduces Serotonin.
    When shooting for waking, the opposite happens. There's a bit of chemical balance there.

    But in swallowing a chunk of it, instead of it being balanced by the brain, you're introducing the melatonin in unbalanced form.
    The brain should still produce less serotonin... but it just isn't the same.

    Think of driving a manual transmission where you feather the clutch. If you don't balance it right, you can get a shudder or a stall.
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