Notices
Results 1 to 11 of 11
Like Tree2Likes
  • 1 Post By mat5592
  • 1 Post By mat5592

Thread: Malaria Vaccine

  1. #1 Malaria Vaccine 
    Forum Masters Degree mat5592's Avatar
    Join Date
    Mar 2013
    Location
    West Virginia
    Posts
    601
    "An investigational malaria vaccine has been found to be safe, to generate an immune system response, and to offer protection against malaria infection in healthy adults, according to the results of an early-stage clinical trial published Aug. 8 in the journal Science.

    To evaluate whether and how well the PfSPZ Vaccine prevented malaria infection, each participant — the vaccinees as well as the control group that did not receive vaccine – was exposed to bites by five mosquitoes carrying the P. falciparum strain from which the PfSPZ Vaccine was derived. This controlled human malaria infection procedure — a standard process in malaria vaccine trials — took place three weeks after participants received their final vaccination. Participants were monitored as outpatients for seven days and then admitted to the NIH Clinical Center, where they stayed until they were diagnosed with malaria, treated with anti-malarial drugs and cured of infection, or shown to be free of infection.

    The researchers found that the higher dosages of PfSPZ Vaccine were associated with protection against malaria infection. Only three of the 15 participants who received higher dosages of the vaccine became infected, compared to 16 of 17 participants in the lower dosage group who became infected. Among the 12 participants who received no vaccine, 11 participants became infected after mosquito challenge."
    Investigational malaria vaccine found safe and protective

    For some reason, I haven't really seen this in the media. Is that because the millions of people that could potentially be saved from this prevalent and deadly disease aren't located in the U.S.? I know if something similar were published about HIV, everyone would be going crazy. Maybe those of you with more experience could tell me if this type of thing (seemingly promising results) happens often and I'm putting too much into this. Also, is it a common practice for people to willingly infect themselves with a disease in the name of science?

    But hey, if this turns out in the long run, maybe one day I won't be afraid to take that dream trip to Africa!

    Edit: Upon further review, I've found a few news sites that mentioned it, all of which are claiming (and I have NO idea where they got this?!) that it's "100% effective." Really? I mean...really??


    Ascended likes this.
    Reply With Quote  
     

  2.  
     

  3. #2  
    Moderator Moderator Cogito Ergo Sum's Avatar
    Join Date
    Jun 2013
    Location
    Belgium
    Posts
    2,507
    Quote Originally Posted by mat5592 View Post
    For some reason, I haven't really seen this in the media.

    Yet, I have found articles (as you have stated in your last sentence) about on the website of ScienceDaily, on Nature News and on Scientific American.
    Zapped Malaria Parasite Raises Vaccine Hopes: Scientific American
    Zapped malaria parasite raises vaccine hopes : Nature News & Comment
    Investigational malaria vaccine found safe and protective

    Quote Originally Posted by mat5592 View Post
    Also, is it a common practice for people to willingly infect themselves with a disease in the name of science?

    Not common, but it has happened. Medical self-experimentation isn't rare in history. Examples are Barry Marshall & Robin Warren (Nobel Prize of Medicine, 2005) and Werner Frossman (Nobel Prize of Medicine, 1956).

    Quote Originally Posted by mat5592 View Post
    I've found a few news sites that mentioned it, all of which are claiming (and I have NO idea where they got this?!) that it's "100% effective." Really? I mean...really??

    Unfortunately, sensation is often more interesting than the truth.


    Source:
    Pickover, C.A. (2012), "The Medical Book: From Witch Doctors to Robot Surgeons, 250 Milestones in the History of Medicine", Sterling Publishing Inc., p. 346


    Last edited by Cogito Ergo Sum; February 7th, 2014 at 06:40 AM.
    "The only safe rule is to dispute only with those of your acquaintance of whom you know that they possess sufficient intelligence and self-respect not to advance absurdities; to appeal to reason and not to authority, and to listen to reason and yield to it; and, finally, to be willing to accept reason even from an opponent, and to be just enough to bear being proved to be in the wrong."

    ~ Arthur Schopenhauer, The Art of Being Right: 38 Ways to Win an Argument (1831), Stratagem XXXVIII.
    Reply With Quote  
     

  4. #3  
    Forum Masters Degree mat5592's Avatar
    Join Date
    Mar 2013
    Location
    West Virginia
    Posts
    601
    Quote Originally Posted by Cogito Ergo Sum View Post


    Quote Originally Posted by mat5592 View Post
    I've found a few news sites that mentioned it, all of which are claiming (and I have NO idea where they got this?!) that it's "100% effective." Really? I mean...really??



    Unfortunately, sensation is often more interesting than the truth.
    That seems to be the case too often these days. People are more worried about breaking a story first and getting the most views instead of reporting the truth.
    Reply With Quote  
     

  5. #4  
    AI's Have More Fun Bad Robot's Avatar
    Join Date
    Apr 2013
    Location
    Washington state
    Posts
    6,114
    Quote Originally Posted by mat5592 View Post
    Quote Originally Posted by Cogito Ergo Sum View Post


    Quote Originally Posted by mat5592 View Post
    I've found a few news sites that mentioned it, all of which are claiming (and I have NO idea where they got this?!) that it's "100% effective." Really? I mean...really??



    Unfortunately, sensation is often more interesting than the truth.
    That seems to be the case too often these days. People are more worried about breaking a story first and getting the most views instead of reporting the truth.
    I found another link you might be interested in. Also per this article it's not 100% effective yet.

    BBC News - Malaria vaccine shows early promise in clinical trials

    I would like to see some articles that talk about the impact this will have a large segment of the world population.
    Reply With Quote  
     

  6. #5  
    Forum Radioactive Isotope skeptic's Avatar
    Join Date
    Nov 2008
    Location
    New Zealand
    Posts
    4,843
    This is the kind of news we should get more of. It will affect more people for a lot longer than those news stories of bizarre murders etc.

    Incidentally, if you want that dream trip to Africa, do not hesitate. Malaria can be made very improbable by taking basic precautions.
    Reply With Quote  
     

  7. #6  
    Forum Masters Degree mat5592's Avatar
    Join Date
    Mar 2013
    Location
    West Virginia
    Posts
    601
    Quote Originally Posted by skeptic View Post
    This is the kind of news we should get more of. It will affect more people for a lot longer than those news stories of bizarre murders etc.

    Incidentally, if you want that dream trip to Africa, do not hesitate. Malaria can be made very improbable by taking basic precautions.
    If the news ever covered anything like this and its implications, I might actually watch more of it. Hearing the same thing over and over about one murder (while there are thousands of others occurring in the meantime, I might add) gets pretty boring pretty quickly. I don't know how it is in New Zealand, though.

    I was kind of kidding with the dream trip to Africa, but it would be cool to travel there and help administer these vaccines once available!
    Reply With Quote  
     

  8. #7  
    Moderator Moderator Cogito Ergo Sum's Avatar
    Join Date
    Jun 2013
    Location
    Belgium
    Posts
    2,507
    Quote Originally Posted by mat5592 View Post
    If the news ever covered anything like this and its implications, I might actually watch more of it. Hearing the same thing over and over about one murder (while there are thousands of others occurring in the meantime, I might add) gets pretty boring pretty quickly. I don't know how it is in New Zealand, though.

    I was kind of kidding with the dream trip to Africa, but it would be cool to travel there and help administer these vaccines once available!

    I just hope that the Anti-Vaccination Movement waives future plans to hinder the administration of the vaccine.
    "The only safe rule is to dispute only with those of your acquaintance of whom you know that they possess sufficient intelligence and self-respect not to advance absurdities; to appeal to reason and not to authority, and to listen to reason and yield to it; and, finally, to be willing to accept reason even from an opponent, and to be just enough to bear being proved to be in the wrong."

    ~ Arthur Schopenhauer, The Art of Being Right: 38 Ways to Win an Argument (1831), Stratagem XXXVIII.
    Reply With Quote  
     

  9. #8  
    Ascended Member Ascended's Avatar
    Join Date
    Apr 2012
    Location
    UK
    Posts
    3,370
    I saw some of this story on the news, a report where they presented a "dumbed down version". They suggested that live malaria parasites were first irradiated and then intravenously administered to volunteers. Now I don't know very much about vaccines but would that kind of practice be normal, to actually put live parasites inside people?
    Everything has its beauty, but not everyone sees it. - confucius
    Reply With Quote  
     

  10. #9  
    AI's Have More Fun Bad Robot's Avatar
    Join Date
    Apr 2013
    Location
    Washington state
    Posts
    6,114
    Quote Originally Posted by Ascended View Post
    I saw some of this story on the news, a report where they presented a "dumbed down version". They suggested that live malaria parasites were first irradiated and then intravenously administered to volunteers. Now I don't know very much about vaccines but would that kind of practice be normal, to actually put live parasites inside people?
    As it stands now I would just avoid going anyplace where it might be needed. However if I lived in an area where half the people or more were infected, I would certainly give it a shot. Malaria is the all time killer of more humans than any other disease, and whatever it takes to control it is good. They don't talk much about the lost productivity of all the infected people that haven't died from it, but it must be in the trillions of dollars. It's no wonder some of those 3rd world countries aren't making more progress than they are.
    Reply With Quote  
     

  11. #10  
    Forum Masters Degree mat5592's Avatar
    Join Date
    Mar 2013
    Location
    West Virginia
    Posts
    601
    Quote Originally Posted by Ascended View Post
    I saw some of this story on the news, a report where they presented a "dumbed down version". They suggested that live malaria parasites were first irradiated and then intravenously administered to volunteers. Now I don't know very much about vaccines but would that kind of practice be normal, to actually put live parasites inside people?
    I'm not aware of any parasitic vaccines, but it is very common for viral/bacterial vaccines to just be weakened, but living versions of the pathogen, like the MMR, Varicella, BCG (tuberculosis, which we don't receive here in the States, but I think it's used in Europe), etc.
    Ascended likes this.
    Reply With Quote  
     

  12. #11  
    Moderator Moderator Cogito Ergo Sum's Avatar
    Join Date
    Jun 2013
    Location
    Belgium
    Posts
    2,507
    Quote Originally Posted by mat5592 View Post
    I'm not aware of any parasitic vaccines, but it is very common for viral/bacterial vaccines to just be weakened, but living versions of the pathogen, like the MMR, Varicella, BCG (tuberculosis, which we don't receive here in the States, but I think it's used in Europe), etc.

    Attenuated vaccines for tuberculosis are indeed used in some European countries (although the regulations for the administration of BCG differ).
    "The only safe rule is to dispute only with those of your acquaintance of whom you know that they possess sufficient intelligence and self-respect not to advance absurdities; to appeal to reason and not to authority, and to listen to reason and yield to it; and, finally, to be willing to accept reason even from an opponent, and to be just enough to bear being proved to be in the wrong."

    ~ Arthur Schopenhauer, The Art of Being Right: 38 Ways to Win an Argument (1831), Stratagem XXXVIII.
    Reply With Quote  
     

Similar Threads

  1. Catholics and the HPV vaccine
    By Golkarian in forum Scientific Study of Religion
    Replies: 34
    Last Post: July 16th, 2011, 02:01 PM
  2. Fungal spores to control malaria mosquito
    By skeptic in forum Biology
    Replies: 0
    Last Post: February 21st, 2011, 01:27 PM
  3. Universal flu vaccine breakthrough
    By Hippocampus in forum In the News
    Replies: 2
    Last Post: February 9th, 2011, 02:10 PM
  4. Hep B vaccine
    By beaver13 in forum Health & Medicine
    Replies: 3
    Last Post: November 15th, 2010, 02:56 PM
  5. Seeking open innovation ideas in malaria and tuberculosis
    By skar in forum Personal Theories & Alternative Ideas
    Replies: 0
    Last Post: February 12th, 2010, 06:30 PM
Bookmarks
Bookmarks
Posting Permissions
  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •