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Thread: Cancers: Another of my Imponderables

  1. #1 Cancers: Another of my Imponderables 
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    Given that millions of body cells multiply daily within the body, I figure the odds are good something can go wrong, maybe oftener than we know. If this latter be true, then, given that now and then, the reproducing process for a certain cell goes "haywire" one time, producing cells which replicate much faster than normal, we soon have a mass of similar cells we did not expect.

    I propose that this occurs much more often than we think, and only occasionally produces an uncontrolled "cancer", since the early-on presentation of "wrong" cells is detected as such by the immune system, which takes action to stop/eliminate the abnormal replication.

    If so, it would explain why some get cancer, while most do not.

    What do you think of that? jocular


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    Your insight is entirely correct. I am an oncologist and have been researching cancer for many years now. As frightening as it may be, it is true that you probably have some cancerous, malignant cells in your body. Don't worry, though, because they probably are not threatening and will not culminate into what we tend to consider "cancer" in its dangerous form. What actually happens is that these cancer cells (and by cancer cells at this stage of the game, we're talking about cells that have lost density dependent inhibition, control of the R-point, usually due to a tumor supressor being downregulated or inhibited) are detected by immune cells and killed by NK cells. The reason that some cancer cells can evade detection is that they have a certain gene(s) that modify the cell surface so that mast cells cannot recognize the cancer cells. Cancer cells that have done this typically need a lot of time to do such an act, and usually succeed in leading to tumors and dangerous cancers.


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    Quote Originally Posted by ScienceRocks View Post
    Your insight is entirely correct. I am an oncologist and have been researching cancer for many years now. As frightening as it may be, it is true that you probably have some cancerous, malignant cells in your body. Don't worry, though, because they probably are not threatening and will not culminate into what we tend to consider "cancer" in its dangerous form. What actually happens is that these cancer cells (and by cancer cells at this stage of the game, we're talking about cells that have lost density dependent inhibition, control of the R-point, usually due to a tumor supressor being downregulated or inhibited) are detected by immune cells and killed by NK cells. The reason that some cancer cells can evade detection is that they have a certain gene(s) that modify the cell surface so that mast cells cannot recognize the cancer cells. Cancer cells that have done this typically need a lot of time to do such an act, and usually succeed in leading to tumors and dangerous cancers.
    Far more fascinating! My insight stems from having had only one course in Biology, some 50+ years ago, and a lot of logical thought. However, having available structured explanatory information of such technical nature as you present, is truly worthy of a Science Forum!

    Thank you most heartily!

    jocular
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    you're quite welcome
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