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Thread: development of inhibitor for an enzyme

  1. #1 development of inhibitor for an enzyme 
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    Hi, I'm a 15 yr old student trying to do a project on developing an inhibitor for the bacterial nitric oxide synthase enzyme using rational drug design methods. The timeframe for this project is around 5 - 6 months for research. Can anyone please give advice on the feasibility and suitability of this current project and perhaps give alternative/narrowed down versions of this project?

    Would it help if I just narrowed our scope to finding out the structure of bacterial nitric oxide synthase using x-ray crystallography/nuclear magnetic resonance etc. sort of methods?

    Thanks a lot!


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  3. #2  
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    I would narrow your topic.
    X-ray crystallography / NMR are vast topics unto themselves

    The exercise of trying to design an enzymatic inhibitor will teach you a lot, good luck.


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  4. #3 Re: development of inhibitor for an enzyme 
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    Quote Originally Posted by inggumnator
    Hi, I'm a 15 yr old student trying to do a project on developing an inhibitor for the bacterial nitric oxide synthase enzyme using rational drug design methods. The timeframe for this project is around 5 - 6 months for research. Can anyone please give advice on the feasibility and suitability of this current project and perhaps give alternative/narrowed down versions of this project?

    Would it help if I just narrowed our scope to finding out the structure of bacterial nitric oxide synthase using x-ray crystallography/nuclear magnetic resonance etc. sort of methods?

    Thanks a lot!
    Inhibiting enzymes is another way to hinder or block it. This could be used on all enzymes if the inhibitor is correct.

    You can inhibit any disease by producing red blood cells, but maybe there is a cheaper more accessible way?

    Bacteria can be found in yoghurt. Yoghurt we can say is like the system it is in. Cooling it down kills it faster, and heating it up excites it. Yor body gets hot when you are sick, yes?

    To kill the bacteria you need to burn it out it. I suggest a sauna or something, or, you could use some chloroform and an assitant that will stick the sauan right up to the maxium suggested heat to kill them quickly. You could do this on a sun bed, or, even better, you could eat a lot of sugar that will burn out and make your system hotter due to processing of fuels in the sugar.

    All you need to save yourself from a disease is a table spoon and some sugar, lots of it!
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  5. #4  
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    Charlatan, are you a bot? Your response fails completely to address any aspect of inggumnator's query. Prove you are not a bot, by providing a meaningful directed response to this challenge.
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  6. #5 Re: development of inhibitor for an enzyme 
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    Quote Originally Posted by Charlatan
    Inhibiting enzymes is another way to hinder or block it. This could be used on all enzymes if the inhibitor is correct.

    You can inhibit any disease by producing red blood cells, but maybe there is a cheaper more accessible way?

    Bacteria can be found in yoghurt. Yoghurt we can say is like the system it is in. Cooling it down kills it faster, and heating it up excites it. Yor body gets hot when you are sick, yes?

    To kill the bacteria you need to burn it out it. I suggest a sauna or something, or, you could use some chloroform and an assitant that will stick the sauan right up to the maxium suggested heat to kill them quickly. You could do this on a sun bed, or, even better, you could eat a lot of sugar that will burn out and make your system hotter due to processing of fuels in the sugar.

    All you need to save yourself from a disease is a table spoon and some sugar, lots of it!
    I have thought it over carefully and decided that this was the dumbest thing I have ever read on a forum.
    Co-producer of Red Oasis
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