Notices
Results 1 to 16 of 16

Thread: Possible Cure for Allergies?

  1. #1 Possible Cure for Allergies? 
    Forum Professor marcusclayman's Avatar
    Join Date
    Mar 2009
    Posts
    1,702
    http://www.sciencedaily.com/releases...0818182100.htm

    In this study, people with allergies to milk were given milk, first in smaller amounts and then more and more, which trained their immune system to tolerate it.

    Some folks still had reactions, but they were generally much less serious.



    For someone who is deathly allergic to something, is there a minuscule(even if microscopic) amount that is safe?

    If so, then pharmaceutical companies should start making prescription allergy "trainers"

    of course, tests need to be done on other allergens



    I have noticed that my outdoor allergies have, all but completely, gone away. This happened after a few years of homelessness, in which I spent much of my time outside.


    Dick, be Frank.

    Ambiguity Kills.
    Reply With Quote  
     

  2.  
     

  3. #2  
    Forum Freshman
    Join Date
    Aug 2009
    Posts
    8
    A very interesting point indeed.
    I wonder though 18 kids , is that enough to perform a study on ?
    I mean , does that count as being representative.


    Reply With Quote  
     

  4. #3  
    Forum Professor marcusclayman's Avatar
    Join Date
    Mar 2009
    Posts
    1,702
    Good point
    Dick, be Frank.

    Ambiguity Kills.
    Reply With Quote  
     

  5. #4  
    Forum Professor
    Join Date
    Sep 2007
    Posts
    1,079
    This was done with peanuts successfully as well. There is some therapy geared towards desensitization using this approach.
    Reply With Quote  
     

  6. #5  
    Reptile Dysfunction drowsy turtle's Avatar
    Join Date
    Mar 2009
    Location
    UK
    Posts
    2,255
    WARNING! DO NOT TRY AT HOME!

    Just in case anyone is reading this and thinking 'hmmmm'.
    "The major difference between a thing that might go wrong and a thing that cannot possibly go wrong is that when a thing that cannot possibly go wrong goes wrong it usually turns out to be impossible to get at or repair." ~ Douglas Adams
    Reply With Quote  
     

  7. #6  
    Reptile Dysfunction drowsy turtle's Avatar
    Join Date
    Mar 2009
    Location
    UK
    Posts
    2,255
    Quote Originally Posted by coincidence
    A very interesting point indeed.
    I wonder though 18 kids , is that enough to perform a study on ?
    I mean , does that count as being representative.
    Milk allergies are generally the same, although I suppose in different people it could be triggered by different allergens. More trials would be needed before it can become a common treatment, but I'd say yes, this is representative.
    "The major difference between a thing that might go wrong and a thing that cannot possibly go wrong is that when a thing that cannot possibly go wrong goes wrong it usually turns out to be impossible to get at or repair." ~ Douglas Adams
    Reply With Quote  
     

  8. #7  
    Forum Cosmic Wizard i_feel_tiredsleepy's Avatar
    Join Date
    Mar 2008
    Location
    Montreal
    Posts
    2,256
    A lot of research on allergy immunotherapy has been done around bee venom. The basic idea is that small doses are safe and can hopefully induce more and more IgG responses to the allergen rather than the typical IgE response typical of allergic disease.

    I have a paper hanging around my house on the subject that I'll try to dig up.
    Reply With Quote  
     

  9. #8  
    Forum Professor marcusclayman's Avatar
    Join Date
    Mar 2009
    Posts
    1,702
    this reminds me of homeopathic therapy... i think that's what it's called

    when incredibly toxic things like cobra venom are diluted a great deal and taken to cure things like cancer

    whether or not it works, I wouldn't know

    but there is a safe level of EVERYTHING, right? safe is a relative term though, of course
    Dick, be Frank.

    Ambiguity Kills.
    Reply With Quote  
     

  10. #9  
    Forum Freshman Incoming Dessert's Avatar
    Join Date
    Aug 2009
    Location
    North Yorkshire, England
    Posts
    81
    The minor snag of homeopathy is that doses are diluted to the level where there is no trace of the original dose left.

    I think I read somewhere that heavy reliance on anti-bacterial surface cleaners and the like is making allergies worse, although I can't quite recall the reasons behind it. Apparently hayfever was almost none existent a few decades ago.
    The wise man believes half of what he reads. If he knew which half to believe, he'd be a much wiser man.
    Reply With Quote  
     

  11. #10  
    Forum Ph.D.
    Join Date
    Aug 2006
    Posts
    792
    Antibacterials do what they say, they kill bacteria, and the theory is that without your everyday bacteria to kill, your immune system becomes hypersensitive and starts mounting an immune response to every day antigens which are harmless, e.g. pollen dustmites etc. This is the hygiene hypothesis whereby too clean an environment increases your IgE levels.
    This is most important in childhood, and there is evidence that when exposed to pathogenic components, e.g. LPS, viral dsRNA or chitin, that via toll like receptors, the immune system favours the Th1 pathway and away from the Th2 pathway which is more prone to allergic type responses.

    I think most of this research was involving the role of bacteria in the digestive tract; I dont know anything about bee toxin but I dont see why it wouldnt promote a similar response.
    marcusclayman; I dont think he was suggesting a role for homeopathy, there is little evidence for its efficacy.

    Hill C, Doyon F. Review of randomized trials of homeopathy. Review of Epidemiology 38:139-142, 1990.
    Reply With Quote  
     

  12. #11  
    Forum Professor marcusclayman's Avatar
    Join Date
    Mar 2009
    Posts
    1,702
    I was not suggesting homeopathy, it just reminded me of it. Now that I think about it, cobra venom is not an allergen. :P
    Dick, be Frank.

    Ambiguity Kills.
    Reply With Quote  
     

  13. #12  
    Forum Cosmic Wizard i_feel_tiredsleepy's Avatar
    Join Date
    Mar 2008
    Location
    Montreal
    Posts
    2,256
    Quote Originally Posted by Robbie
    Antibacterials do what they say, they kill bacteria, and the theory is that without your everyday bacteria to kill, your immune system becomes hypersensitive and starts mounting an immune response to every day antigens which are harmless, e.g. pollen dustmites etc. This is the hygiene hypothesis whereby too clean an environment increases your IgE levels.
    This is most important in childhood, and there is evidence that when exposed to pathogenic components, e.g. LPS, viral dsRNA or chitin, that via toll like receptors, the immune system favours the Th1 pathway and away from the Th2 pathway which is more prone to allergic type responses.

    I think most of this research was involving the role of bacteria in the digestive tract; I dont know anything about bee toxin but I dont see why it wouldnt promote a similar response.
    marcusclayman; I dont think he was suggesting a role for homeopathy, there is little evidence for its efficacy.

    Hill C, Doyon F. Review of randomized trials of homeopathy. Review of Epidemiology 38:139-142, 1990.
    Indeed, there is even evidence that certain isoforms of TLR have been linked to genetic predispositions to asthma. Immunology is heavy duty stuff to approach though. If we start to get into a discussion of TLRs and cytokines we're gonna lose pretty much everyone except Biologista.
    Reply With Quote  
     

  14. #13  
    Forum Ph.D.
    Join Date
    Aug 2006
    Posts
    792
    yeah dont worry, I dont know enough about toll like receptors and how they work to discuss anything properly!
    Reply With Quote  
     

  15. #14  
    Forum Ph.D. Darius's Avatar
    Join Date
    Jan 2009
    Posts
    817
    Quote Originally Posted by i_feel_tiredsleepy
    If we start to get into a discussion of TLRs and cytokines we're gonna lose pretty much everyone except Biologista.
    You would not lose me, either. Do discuss the concept, as I am intrigued.
    Om mani padme hum

    "In dishonorable things we are not bound to obey any man." - The Book of the Courtier [1561], pg 99 (144 in pdf)
    Reply With Quote  
     

  16. #15  
    Forum Professor marcusclayman's Avatar
    Join Date
    Mar 2009
    Posts
    1,702
    If it's interesting enough, I don't mind studying to understand new things... that's why I'm on this forum

    go on
    Dick, be Frank.

    Ambiguity Kills.
    Reply With Quote  
     

  17. #16  
    Forum Radioactive Isotope skeptic's Avatar
    Join Date
    Nov 2008
    Location
    New Zealand
    Posts
    4,843
    I always like to remind people of the first law of toxicology.

    The dose makes the poison.

    This means two things.
    1. Everything is harmless in a small enough dose. For example : the most lethal substance ever discovered is the poison made by the bacterium Clostridium botulinum. Yet in minute doses we inject it into the faces of women, as botox.

    2. Everything is lethal at a big enough dose. For example; we have all heard of the cases where party going people take the drug ecstasy, which induces a big thirst. These party goers have been known to drink so much water, they die. Even water is extremely harmful if the dose is big enough!

    The same principles apply to allergies. If a small enough amount of allergen is applied to an allergic person, it does no harm. If this dose is slowly increased over time, it gives the body a chance to adapt. As others have said, this technique has been tried and demonstrated to work for a range of allergies.
    Reply With Quote  
     

Bookmarks
Bookmarks
Posting Permissions
  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •