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Thread: Focusing on only one oncoprotein a waste of cancer research money???

  1. #1 Focusing on only one oncoprotein a waste of cancer research money??? 
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    It is WELL documented, from research dating back to before the year 2000 from gene transfection methods, that activation of one oncoprotein (either proto-oncoprotein or pure non-proto-oncoprotein) cannot induce cancer in a cell alone. At the very least, two or more oncoproteins need to be induced in a normal cell to induce cancer. There are many dollars of research going towards better understanding what happens as certain proteins are turned into proto-oncoproteins (such as Ras and p53). Should research money be spent on seemingly more promising therapeutic methods, such as immunology, or should money still be spent on better learning about single oncoproteins, when the activation of one oncoprotein alone cannot induce cancer (granted, it may behoove researchers to fund oncoprotein research since many different labs study many different oncoproteins). Sorry if this question is wordy or confusing.


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    Should research money be spent on seemingly more promising therapeutic methods, such as immunology, or should money still be spent on better learning about single oncoproteins, when the activation of one oncoprotein alone cannot induce cancer
    Surely if it requires two events accumulating to initiate cancer, finding a way to deactivate or prevent one of them means that the other remains harmless.

    That'd be a good outcome if it works.


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