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Thread: Stimulating Mitochondrial Growth Artificially?

  1. #1 Stimulating Mitochondrial Growth Artificially? 
    Forum Freshman Tony John C's Avatar
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    Would it even be possible to stimulate mitochondrial growth artificially to enhance endurance? I do know that naturally during exercise you secrete a chemical of somekind that does stimulate mitochondrial formation. I've also read that Ca2+ used intermittenly will cause some stimulation, but is there anymore research being done to see what else may cause similar effects. If so could you point me in the right direction.


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    Forum Cosmic Wizard paralith's Avatar
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    Sounds like a plausible research avenue to me, though I can't recall anything specific off the top of my head. Try doing a google scholar or pubmed search, I bet you could find quite a few papers on the subject.


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  4. #3 Re: Stimulating Mitochondrial Growth Artificially? 
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    Quote Originally Posted by Tony John C
    Would it even be possible to stimulate mitochondrial growth artificially to enhance endurance? I do know that naturally during exercise you secrete a chemical of somekind that does stimulate mitochondrial formation. I've also read that Ca2+ used intermittenly will cause some stimulation, but is there anymore research being done to see what else may cause similar effects. If so could you point me in the right direction.
    Try a google search on "Mitochondrial health." There is a good deal of research in this area.
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    Forum Freshman Tony John C's Avatar
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    Thanks guys. I would have posted earlier, but I was busy writing papers for my classes. Quite annoying. =D
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  6. #5 Re: Stimulating Mitochondrial Growth Artificially? 
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    Quote Originally Posted by Tony John C
    Would it even be possible to stimulate mitochondrial growth artificially to enhance endurance? I do know that naturally during exercise you secrete a chemical of somekind that does stimulate mitochondrial formation. I've also read that Ca2+ used intermittenly will cause some stimulation, but is there anymore research being done to see what else may cause similar effects. If so could you point me in the right direction.
    Good question. I'd like to know m'self.
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    Administrator KALSTER's Avatar
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    We exhale most of the oxygen we inhale again, so would the increase in mitochondria increase diffusion into cells, or is it simply that enough diffuses into the cell, but there is not enough mitochondria to use it?
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    Forum Cosmic Wizard spuriousmonkey's Avatar
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    our mitochondria are apparently already geared up compared with chimps. Anyting affecting our mitochondria is going to cause major problems in the brain.

    Because we have created this huge energy wasting brain, that craves for more and more energy.

    then again, i read it in a popular science book so it might not be true.
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  9. #8  
    Forum Freshman Tony John C's Avatar
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    Quote Originally Posted by spuriousmonkey
    our mitochondria are apparently already geared up compared with chimps. Anyting affecting our mitochondria is going to cause major problems in the brain.

    Because we have created this huge energy wasting brain, that craves for more and more energy.

    then again, i read it in a popular science book so it might not be true.
    Yea, but mitochondria numbers have direct impact on endurance. Instead of the body using anaerobic respiration, with more mitochondria it becomes nearly all aerobic respiration. Mitochondria also have a 4 to 5 day life span, i which they will break down. This is why if you take a week off from running you feel at square one. If athletes have raised mitochodrial numbers, I'm asking if we could artificially raise a person to that status without the rigorous training, and no taking off. To gain and maintain peak endurance.

    What do you mean by energy wasting brain? How much on average energy do humans use in comparison to chimps?
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    Forum Cosmic Wizard spuriousmonkey's Avatar
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    Quote Originally Posted by Tony John C
    What do you mean by energy wasting brain? How much on average energy do humans use in comparison to chimps?

    I can't find figures on the chimp brain energy consumption so quickly, but we can extrapolate of course.

    The human brain is 1/50 of the body size weight, but uses up to 20% of the metabolic resources.

    The human brain is on average 1300gr. The chimps 300-500gr.
    Chimp stats Size: Height: 170 cm. Females: 130 cm: Weight: 45 - 80kg.
    The areas that grew most rapidly in humans are probably also the most energy consuming.

    I guess the energy use can be at least double as much based on size alone, or more.

    Any defect to the artery that supplies the brain has huge consequences for human brain development. The same defects in the chimp have little or no consequences.
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