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Thread: cross-species genetics

  1. #1 cross-species genetics 
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    Cross species genetics, Hybrid(Biology) and Neurogenetics.
    Biology is not my strong suite nor am I fond of it. However after reading a few articles, as per suggested by my colleagues, a question came up in my mind, "Is it possible for man to cross-breed with animals?"
    Well is it possible? if so please elaborate.
    I developed an interest in this subject.I don't know where to start. Can anyone please refer to me some readings, books and articles related to this topic. Thank You!

    -Marie


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    Forum Sophomore M_Gabriela's Avatar
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    Hello. Humans can not cross breed with other species that are not humans. Human sperm have a type of protein in the cell surface that must interact with proteins from oocyte surface. This interaction triggers the fertilization. Sperm from other animals do not have those specific proteins, so they could never fertilize the human oocyte. That is one of the most important barriers of human reproductive isolation.

    But this type of reproductive isolation doesnīt happen for all species. For example, a female horse can reproduce with a male donkey. They are two different species but close though, so in this particular case fertilization can occur. When it does (happen), the offspring (a mule) will have a different number of cromosomes than its parents. In fact, mules are sterile because of this.


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    I see, however is it entirely impossible to alter a sperm such that it may fertilize an egg of an entirely different species?
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    ... Perhaps some sort of retrovirus or similar could inject DNA from other species? I don't really see how it would be possible to physically alter a sperm cell. Though I admit it would be awesome(ly cool and probably dangerous) to see what would happen. How it would look would depend on what chromosomes it got; if it got the genes for body structure from a human it would look like a human, the same for if it got the genes for body structure from another animal. I'm curious as to how speech would turn out; if they couldn't speak English, or at all, it would be a real-life example of the trope "And I Must Scream", which I imagine would be terrifying.
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    Quote Originally Posted by Marie View Post
    I see, however is it entirely impossible to alter a sperm such that it may fertilize an egg of an entirely different species?
    Even if you could do that, the cromosomic dosage would not be equilibrated and the individual would not be able to develop, so the mother would have an abortion; if the egg was human.

    If the egg was from another specie and the sperm was human... I donīt really know...
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  7. #6 Cross species genetics 
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    Quote Originally Posted by Marie View Post
    Cross species genetics, Hybrid(Biology) and Neurogenetics.
    Biology is not my strong suite nor am I fond of it. However after reading a few articles, as per suggested by my colleagues, a question came up in my mind, "Is it possible for man to cross-breed with animals?"
    Well is it possible? if so please elaborate.
    I developed an interest in this subject.I don't know where to start. Can anyone please refer to me some readings, books and articles related to this topic. Thank You!

    -Marie
    Hey Marie this can actually be performed right if the conductors of the experiment do it good enough say if someone ha cancer and there wasn't a cure and stem cells still aren't approved , a zebra fish has the ability to regenerate any lost cell or damaged organ and it could actually help because you don't need sperm to perform this operation because you can put the two sets of dna together and make a person who is immune to that cancer.
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    Quote Originally Posted by Marie View Post
    Cross species genetics, Hybrid(Biology) and Neurogenetics.
    Biology is not my strong suite nor am I fond of it. However after reading a few articles, as per suggested by my colleagues, a question came up in my mind, "Is it possible for man to cross-breed with animals?"
    Well is it possible? if so please elaborate.
    No, not conventionally. However, it is possible to genetically alter somatic cells to:
    -add traits not present in the original organism (i.e. the experiment where they made cats glow in the dark by adding jellyfish sequences)
    -fix genetic defects (i.e. mitochondrial replacement therapy)

    Quote Originally Posted by Kynan View Post
    Hey Marie this can actually be performed right if the conductors of the experiment do it good enough say if someone ha cancer and there wasn't a cure and stem cells still aren't approved , a zebra fish has the ability to regenerate any lost cell or damaged organ and it could actually help because you don't need sperm to perform this operation because you can put the two sets of dna together and make a person who is immune to that cancer.
    No, you can't.
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    Forum Professor Zwolver's Avatar
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    Quote Originally Posted by Kynan View Post
    Hey Marie this can actually be performed right if the conductors of the experiment do it good enough say if someone ha cancer and there wasn't a cure and stem cells still aren't approved, a zebra fish has the ability to regenerate any lost cell or damaged organ and it could actually help because you don't need sperm to perform this operation because you can put the two sets of dna together and make a person who is immune to that cancer.
    I thought they use zebrafish for experiments because they grow fast, are easy to breed/keep, transparent eggs, and semi transparent fish. I don't think a zebra fish has any other qualities that other fish don't have.

    You are talking about cloning i guess. But cloning while using two different species has not ever been done as far as i know. And i wouldn't start with two species that are as different as a human is from a fish.. I would start with mouse/rat hybrid or something like that. But even then, you would need to make the rat and the mouse have the same number of chromosomes. That would take some tinkering.

    There is however no species on the planet that doesn't get cancer. Some have more resistance, some have less, but it would insinuate that nature didn't come up with a cure yet. So a hybrid wouldn't solve anything.
    Growing up, i marveled at star-trek's science, and ignored the perfect society. Now, i try to ignore their science, and marvel at the society.

    Imagine, being able to create matter out of thin air, and not coming up with using drones for boarding hostile ships. Or using drones to defend your own ship. Heck, using drones to block energy attacks, counterattack or for surveillance. Unless, of course, they are nano-machines in your blood, which is a billion times more complex..
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