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Thread: Cell signaling: Calcium

  1. #1 Cell signaling: Calcium 
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    Why did cells have evolve intracellular calcium stores for signaling even though there is an abundant extracellular amount of calcium? What is the differential between the amount of calcium inside and outside of the cell at basal levels?


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  3. #2  
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    I wikied physiology and cell chemistry. All that I could find on calcium use in signaling was at the synapses at the muscle connection to inhibit muscles.


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  4. #3  
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    From the wikipedia article: "Movement of calcium ions from the extracellular compartment to the intracellular compartment alters membrane potential. This is seen in the heart, during the plateau phase of ventricular contraction. In this example, calcium acts to maintain depolarization of the heart. Calcium signaling through ion channels is also important in neuronal synaptic transmission."

    Does this answer your question?

    I can't find anything in regard to your second question, and this isn't my area of expertise, so I'll leave that to someone else. Good luck =)
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  5. #4  
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    Thank you.
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