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Thread: What's the pH of DNA?

  1. #1 What's the pH of DNA? 
    Forum Professor Daecon's Avatar
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    This is probably a really silly question, but if DNA is an acid, would it have a pH value?

    Also (probably an even sillier question) I'm presuming the chemical formula of each molecule of DNA is different so would they have different pH values depending on whatever species the DNA is from?


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    I would guess that it would vary for dna, since PH is usually defined as the the amount of hydrogen ions released in water. I'm guessing at that because dna is usually in motion, and if put in water would release how many hydrogens. I'm guessing that it would vary. It is interesting, as both a tree leaf and a toe nail contain dna. You could measure both with a color chang strip. PH acidity is important in chemistry. To make a homade color changing strip, chop up purple cabbage, strain it keep the purple water. Dip paper in the purple water and let it dry, for a homemade color changing strip.


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  4. #3  
    Cooking Something Good MacGyver1968's Avatar
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    Quote Originally Posted by sapien View Post
    I would guess that it would vary for dna, since PH is usually defined as the the amount of hydrogen ions released in water. I'm guessing at that because dna is usually in motion, and if put in water would release how many hydrogens. I'm guessing that it would vary. It is interesting, as both a tree leaf and a toe nail contain dna. You could measure both with a color chang strip. PH acidity is important in chemistry. To make a homade color changing strip, chop up purple cabbage, strain it keep the purple water. Dip paper in the purple water and let it dry, for a homemade color changing strip.
    I would guess you're probably dead wrong...because you always are. (even though I know nothing on the subject)
    Fixin' shit that ain't broke.
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    PHD; Ignore this too. You are not even a chemist.
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    PhDemon, the reason I said your not a chemist is because every time there is a question on chemistry, all you seem to know about it is the ph of water by the numbers if you look it up and if it is gasious liquid or solid and is mixed with salts dirt or an unknown substance or something. Chemisty, organics, biochemistry also contain water.
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    Forum Masters Degree mat5592's Avatar
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    Quote Originally Posted by sapien View Post
    PhDemon, the reason I said your not a chemist is because every time there is a question on chemistry, all you seem to know about it is the ph of water by the numbers if you look it up and if it is gasious liquid or solid and is mixed with salts dirt or an unknown substance or something. Chemisty, organics, biochemistry also contain water.
    What?
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  8. #7  
    Your Mama! GiantEvil's Avatar
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    Quote Originally Posted by sapien View Post
    PHD; Ignore this too. You are not even a chemist.
    The real chemist should be able to answer the following question;
    Given a principal quantum number of 2, and the azimuthal quantum number of 1, and the magnetic quantum number of -1, and the spin quantum number of -1/2.
    What atomic element has been specified?

    Not that the competent should be bothered with demonstrating such in the face of incompetent non-challenges.
    I was some of the mud that got to sit up and look around.
    Lucky me. Lucky mud.
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    I'm not a chemist, but I'm going to take a guess. Helium? Probably wrong. I would have guessed hydrogen except that it had more than one valience level.
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  10. #9  
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    DNA by itself doesn't have a pH.
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    To the original question from Deacon. Cellular PH is lower than the extracellular due to the chemical content. For that DNA being inside the cell would be relatively acidic. Water has a PH of 7. The lower the PH the more acidic, and the higher the ph the more alcaline. I think its due to the cloride in the cell.
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    Oh dana boy......... pah hoopa pah hoopa............and I do mean ...Pahoopah
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    Moderator Moderator Markus Hanke's Avatar
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    Quote Originally Posted by Max Goldstein View Post
    Oh dana boy......... pah hoopa pah hoopa............and I do mean ...Pahoopah
    MODERATOR WARNING : Please refrain from posting gibberish such as the above, or else your presence on this forum will be short lived.
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  14. #13  
    Brassica oleracea Strange's Avatar
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    Quote Originally Posted by sapien View Post
    as both a tree leaf and a toe nail contain dna
    That can't be true.
    Without wishing to overstate my case, everything in the observable universe definitely has its origins in Northamptonshire -- Alan Moore
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    es planes a lot demone. if i had a chemistry question i wouldn't ask a wannabe supiorier than troll like you
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    PhDemon; Please disregard that last post and I apolgise as I thought you were a yank when after all you are probably one of the best chemists England has and a respectable member of the royal society of chemistry. Have a nice day.
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  17. #16  
    Forum Junior anticorncob28's Avatar
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    Why did sapien get suspended?
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  18. #17  
    Your Mama! GiantEvil's Avatar
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    Forum Sophomore M_Gabriela's Avatar
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    Quote Originally Posted by GiantEvil View Post
    Quote Originally Posted by sapien View Post
    PHD; Ignore this too. You are not even a chemist.
    The real chemist should be able to answer the following question;
    Given a principal quantum number of 2, and the azimuthal quantum number of 1, and the magnetic quantum number of -1, and the spin quantum number of -1/2.
    What atomic element has been specified?

    Not that the competent should be bothered with demonstrating such in the face of incompetent non-challenges.
    Is it lithium?? hahahaha. Noooo, is not lithium... is Nitrogen... I forgot to consider n=1, l=o, m=0. Dd I do it right?? Man, I should know this things... hahaha

    Poor guy... they never answered the question. DNA has phosphodiester bonds, meaning you have phosphate group...
    Because phosphoric acid is poliprotic, we should see what´s the status of the acid in distilled water...supposing you want to know the pH of acid when it is purified. Looking at the pKa of phosphoric acid (2,7,12), tells us that at neutral pH two protons were released... so you have a higher concentration of protons, so it is acidic.

    But...... in a phosphodiester bond, you have only 1 hidrogen left... It doesn´t change anything. At nutral pH that hidrogen will be realeased, so the consequence is the same... you have an acidic solution. Also that is the reason why DNA has a negative charge. It comes from the phosphate group.

    bye
    Last edited by M_Gabriela; October 2nd, 2014 at 06:25 AM.
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