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Thread: acentric chromosome

  1. #1 acentric chromosome 
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    how do acentric chromosomes take part in cell division when they don't have centromere at all.


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  3. #2  
    Moderator Moderator Cogito Ergo Sum's Avatar
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    Acentric chromosomes do not take part in cell division, nor are they inherited.
    They will not be dragged to either pole at anaphase of mitosis (or meiosis) and will not be incorporated into either progeny nucleus.


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  4. #3  
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    but doesn't it affect the number of chromosome?
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    ***** Participant Write4U's Avatar
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  6. #5  
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    It was always my impression that acentric chromosomes were transmitted unstably to the progeny. That is, the acentric chromosome (ie. a chromosomal fragment) is not able to be controlled by the spindle, but it can still be inherited and for this reason certain irradiated cells could yield daughter cells with chromosome duplications (there are several mechanisms by which this can occur, one of which I had always assumed, perhaps wrongly, was random inheritance of a chromosomal fragment) or with hemizygous regions of the genome.

    Maybe I was always wrong and the fragment is not incorporated into the nucleus, thus subject to degradation in the cytosol.... Anyone able to clarify this for me?
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  7. #6  
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    They aren't inherited. They would become micronudeus and disappear at last. And sometimes the telomeres will also perform the funtion of centromere……
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