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Thread: Cure for age, how unlikely?

  1. #1 Cure for age, how unlikely? 
    Forum Ph.D. Raziell's Avatar
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    Hey.

    Theres are more than enough discussions regarding senescence. What Im more curious about is how likely or unlikely the goal of curing age at all is (If you were to take an educated guess). Is progress actually being made? And what are the major obstacles (in layman's terms).


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    A singular cure for Ageing? Incredibly unlikely.The ageing phenomenon is multifaceted, involving pretty well every organ system, tissue and cell type in the body. It therefore seems unlikely that one factor is causal. Knock out of certain specific genes has been shown to extend life and health span in animal models, shoring up the possibility of use of specific inhibitors to combat the ageing phenotype. The need to enhance health span is undoubted, whilst longevity is invreasing in the Western world and populations ageing, the disparity with health span is widening. My guess is that we will be able to improve health span moderately in the coming years, as a result of research in the field of ageing. Best wishes, Tri.


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    The cure for ageing would not be beneficial to mankind. If we didn't age people wouldn't die naturally causing a surge in the population which is already crowded in some countries.(E.g China)
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    We could use that excuse for many life saving procedures.

    We've nearly doubled average lifespans in the past century and making good progress; it should continue.

    Personally quality of life is a lot more important. A full healthy and active life of 75 years is a lot better than 60 good years and another 50 severe hampered by disability. (insert Neil Young tune)
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    Quote Originally Posted by Dillan3107 View Post
    The cure for ageing would not be beneficial to mankind. If we didn't age people wouldn't die naturally causing a surge in the population which is already crowded in some countries.(E.g China)
    correct. Immortality is personally advantageous but racially disasterous. Evolution is the name of the game, and death drives evolution.
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  7. #6  
    WYSIWYG Moderator marnixR's Avatar
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    the title of this thread appears to imply that age is a disease - it is not, it's more like the way a piece of machinery wears after prolonged usage
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    Quote Originally Posted by marnixR View Post
    the title of this thread appears to imply that age is a disease - it is not, it's more like the way a piece of machinery wears after prolonged usage
    I agree with what you are all saying, but isn't it one of both? Immortality (clinical at least) should be possible. For a price of sterilisation offcourse, i'd pay that price to stop aging right now any day.

    But what is aging?
    - Reducing telomeres in DNA.
    - Cellular clogging.
    - Reduction of collagens, reduction of binding onto collagens.
    - Building residue's. Like cholesterol on the cell membrane.
    - Parasitic or viral cysts. Everyone has thousands of these.
    - DNA mutation rate skyrockets.
    - Less efficient protein production.
    - Build up of toxins.
    - etc etc..

    This can not, or probably not be reversed the way we want. Though creating a mature clone (genetically enhanced offcourse), then transferring our concience to this drone, will grant uss clinical immortality. Ethical stuff on the side this time.
    Growing up, i marveled at star-trek's science, and ignored the perfect society. Now, i try to ignore their science, and marvel at the society.

    Imagine, being able to create matter out of thin air, and not coming up with using drones for boarding hostile ships. Or using drones to defend your own ship. Heck, using drones to block energy attacks, counterattack or for surveillance. Unless, of course, they are nano-machines in your blood, which is a billion times more complex..
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    If individuality, continuity of self and separateness from others wasn't so important to us you could argue that we are already immortal. I'm about 3 billion years old already - there's just that annoying regeneration phase now and again to spoil things.

    Anyway, I'd say aging is an engineering problem, meaning that there's nothing on the theoretical side of things that would prevent us from being biologically immortal; no laws of physics violated kind of thing.
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    I don't understand this desire for immortality. I do understand the desire for a long and healthy life, but that's a different matter.

    Death is automatically part of life - we are animals after all. I can't imagine what people think they'll be doing when they're 250 or 400 years old.

    Who will be your friends? How healthy and vigorous will you be? What useful work will you do? Where will you and a few billion of your double century years old friends live? What will you eat? Will you expect your great-great-great-great-great-grandchildren to celebrate your birthday with you? How does conservation of matter work when one living species keeps on keeping on?

    I'd much rather die (preferably in my sleep, but at least not too slow or too hard) after doing the right thing by children, grandchildren, friends and relatives and feeling that my life was worthwhile to the people I knew. With any luck, I'll find somewhere to be buried where my bits and pieces will find their natural way back into the cycle of life through plants and trees. We can't just take - and keep on taking - from the cycles of life and death of plants and animals that support us. At some point we must give up and give back.
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    Quote Originally Posted by adelady View Post
    I don't understand this desire for immortality.
    may i suggest it comes from a very human desire to find out what happens next ? like dipping to the back of a book to see how it ends
    apart from the fact that life's story never ends, obviously
    "Reality is that which, when you stop believing in it, doesn't go away." (Philip K. Dick)
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  12. #11  
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    Quote Originally Posted by adelady View Post
    I don't understand this desire for immortality. I do understand the desire for a long and healthy life, but that's a different matter.

    Death is automatically part of life - we are animals after all. I can't imagine what people think they'll be doing when they're 250 or 400 years old.
    adelady, I have read many of your posts and I must say you appear to have wide knowledge in the hard science subjects.
    Having said that I don't really understand your post! What is so special and "natural" about living a "long" and healthy life for say 80 to 90 years? I would not wish to live 200 to 250 years if I was simply being kept alive, by medical science, whilst the ageing process carried on as before, but I would wish to live much longer if this process could be slowed down. I'm pretty sure this will happen in the future and, although this is speculation, even immortality may be a possibility. Arthur C. Clarke believed it would happen and in the not too distant future!
    Obviously if humans were to live much longer it would cause even greater problems in terms of world population, and pressure on scarce resources, but that, in itself, would not alter the wish of many individuals to live much longer lives. I don't feel this desire to be, in the slightest sense, odd. There are only two options for humans; life and consciousness or death, and loss of consciousness, for as long as time exists, and that could be a truly infinite period.
    If, like the British actor George Sanders, you get bored after 400 years (a much longer life than he had) I'm sure a variety of quick and painless methods of suicide will be readily available
    .
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  13. #12  
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    What is so special and "natural" about living a "long" and healthy life for say 80 to 90 years?
    Well, that's normal for both sides of my family. In fact, it's a rule. If you don't make it past 85, then you just haven't tried.

    And it's much the same for my kids. When the youngest arrived, my husband and I were 41 and 36 - and the kids still had all 4 grandparents and 3 great-grandparents for the first few years of their lives. They still had both my parents when the youngest turned 21. My mother's still going strong at 87.
    "Courage is what it takes to stand up and speak; courage is also what it takes to sit down and listen." Winston Churchill
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    I for one could easily live to 500 and still have plenty of stuff to do so long as I was healthy. (probably why I'll never retire, and even resent the idea)
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    And, if we were immortal, we could post on the forum forever
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    Quote Originally Posted by Lynx_Fox View Post
    I for one could easily live to 500 and still have plenty of stuff to do so long as I was healthy. (probably why I'll never retire, and even resent the idea)

    Meteorologist/Naturalist & Retired Soldier
    Sorry, i just like this poking.

    Quote Originally Posted by tridimity View Post
    And, if we were immortal, we could post on the forum forever
    And OMG, i would not like this. Not at all. In 10 years i want to be off this kinds of forums and be exploring the world, and all it's ritches.

    If i were immortal, i would meditate on a pole, for thousands of years, and pretend to be a statue, just for fun.
    Growing up, i marveled at star-trek's science, and ignored the perfect society. Now, i try to ignore their science, and marvel at the society.

    Imagine, being able to create matter out of thin air, and not coming up with using drones for boarding hostile ships. Or using drones to defend your own ship. Heck, using drones to block energy attacks, counterattack or for surveillance. Unless, of course, they are nano-machines in your blood, which is a billion times more complex..
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  17. #16  
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    I am immortal. I am westwind. You will find me everywhere. In Cemeteries, in crowded City Streets. On your Camping Trips, and when you are sailing. I shall stir the seas, rustle the leaves, and bring rain. I am 78 years young. I've made my peace with myself. There will be no squirming or simpering when my time is up, for I have attempted my best throughout my life. And I have observed. Had a look at everything. very little in Life as we humans live it rates a second glance. How to live longer? Why? But if you must, the best of nourishment and plenty of it coupled with consistant and gentle exercise. Like looking after your Vegetable patch, breaking in wild horses, riding your push bikes up mountains, and joining your local Red Cross organisation. Keep out of Gyms---thats all bullshit. And finally, love somebody who loves you back. without this final piece of advice you have no chance of making it. Now, for the first day of the rest of your long life, go outside and take a good breath of westwind. westwind.
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    Quote Originally Posted by adelady View Post
    I don't understand this desire for immortality.
    Maybe it's not so much a desire for life, but a fear of death. You have two choices, experiencing the world... or eternal oblivion. Death and eternity are good friends, best friends. But life? That's just one relationship it's actually impossible to make. So, maybe I can't live forever, but I'd like to live as long as possible. If the technology is readily available, why not? Think of all the great feats and times humanity has yet to achieve; I'd like to see all that.
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    So halorealm, you'd like to see all that. I'm afraid that's not good enough. If life was designed for Spectators we would all have big arrsses. I know what you meant halorealm, and I guess thats OK too, but you are not here primally to observe, not fultime anyway. Great Ships are built in Dry Dock. When they exist, then they begin their lifes journey. You must create your reason for being here, be it useful or otherwise. Can you sing? Can you dance? Can you write? Can you read Poetry in Public?, Can you run?, can you set up a Cabin Accommodation Business in the Wilds of Illinois? Drive a School Bus? Become a rag and bone man? If you have a long Life do not have anyone say at your Funeral, Quote '' Along Life was wasted on Him/Her. '' end Quote. westwind.
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    westwind, don't worry. I wouldn't spend my entire existence just watching stuff. I was just pointing that out as one of the reasons I would live longer particularly. Besides that, even though it's impossible to see everything, you could see a lot more that this relatively short life can't sustain. Life isn't so much a rush anymore.
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  22. #21  
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    Dear halorealm. Quote "" Life isn't so much a rush anymore "" end Quote. How come I wasn't told? I've been busting my FXCHNIZQ gutz all this time when I could have been laid back and FXCHNIZQ resting. No wonder I've got old quick. westwind.
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    Quote Originally Posted by marnixR View Post
    Quote Originally Posted by adelady View Post
    I don't understand this desire for immortality.
    may i suggest it comes from a very human desire to find out what happens next ? like dipping to the back of a book to see how it ends
    apart from the fact that life's story never ends, obviously
    The thing is, dieing IS that last page, if you never die, you're in suspense for the last page. Thing is, you'll never get to it unless you die.
    YOUR life story ends though, but it can't end if you just keep adding forever to it. (when you're immortal.) Seriously, after the 7000th year, I would get bored, and just want to die.
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  24. #23  
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    OK. What we are looking at here is a useful span of existance to enable us to put everything right and in its proper place. To experience all there is to experience. Our problem centres around being curious. We do not have this trait because we are Human, all Life is curious. We are all seekers. We want to continue to participate. Now, why is this? This curiosity? Shouldn't we have been biologically programmed to seek termination of our existance? When we have obviously aged to the point where our usefulness no is longer relevant? We reluctantly are led to the Crematorium. This curiousity factor may just be there to keep us going till we age. But it dosn't switch off, or does it? Life has become complicated. Tecnology keeps updating Life Styles, a different aspect nearly every day. We don't know our place anymore. All this is confusing to us because we spend our time trying to adapt to different circumstances instead of just living an ordinary life as happened when we were Hunters and Gatherers. There are now few touch stones in place to give us stability, give us time to just poke about and Gazing off into Space. westwind.
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    I think I found a cure for age. I was 15 for what seemed like ages and ages. It was really a pain and quite bothersome. But I seem to have beaten that age and am now older and wiser. Hope this helps.
    It is by will alone I set my mind in motion.
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    We mean age as the proces, not a certain age.. As i have also beaten the 80's, 90's, 00's and going on to the 10's..
    Growing up, i marveled at star-trek's science, and ignored the perfect society. Now, i try to ignore their science, and marvel at the society.

    Imagine, being able to create matter out of thin air, and not coming up with using drones for boarding hostile ships. Or using drones to defend your own ship. Heck, using drones to block energy attacks, counterattack or for surveillance. Unless, of course, they are nano-machines in your blood, which is a billion times more complex..
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    Shouldn't we have been biologically programmed to seek termination of our existance?


    Unfortunately, the evolutionary process does not care about human comfort (or about anything, for that matter). A possible evolutionary explanation for the almost insatiable appetite for life that grips the vast majority of us (at least, until our very last moments) is positive selection of organisms that possess such an appetite for life and therefore stick around long enough to help rear their genetic descendents. Just a hunch.

    There are now few touch stones in place to give us stability, give us time to just poke about and Gazing off into Space
    Yep, unfortunately society has styled us all to 'require' a purpose to perpetually validate our existence. Being for the sake of being doesn't enter the consciousness of most people.
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    Quote Originally Posted by Lynx_Fox View Post
    I for one could easily live to 500 and still have plenty of stuff to do so long as I was healthy. (probably why I'll never retire, and even resent the idea)
    Me too. I'd live in different places every few years, do different jobs, visit different places, etc. There are so many things I'd love to give a try and be able to focus on when I want to.
    Disclaimer: I do not declare myself to be an expert on ANY subject. If I state something as fact that is obviously wrong, please don't hesitate to correct me. I welcome such corrections in an attempt to be as truthful and accurate as possible.

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    Me too. I'd live in different places every few years, do different jobs, visit different places, etc. There are so many things I'd love to give a try and be able to focus on when I want to.
    If the many worlds theory is correct, this may already be achieved.
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  30. #29  
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    Quote Originally Posted by Zwolver View Post
    We mean age as the proces, not a certain age.. As i have also beaten the 80's, 90's, 00's and going on to the 10's..
    I was kidding :P *facepalm*
    It is by will alone I set my mind in motion.
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