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Thread: aneuploid hybrid cats

  1. #1 aneuploid hybrid cats 
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    Hello My friend and I are cross breeding a female geoffrey's cat to a male f4 bengal (domestic cat at this point). The problem is that geoffrey's cat has a different number of chromosomes than the domestic bengal. The geoffrey's has 36 while the domestic has 38. This should give the resulting hybrid 37 right? Now this cross has been done the other way numerous times to make what is called the safari cat. In this cross a male geoffrey's is mated to a female domestic. It produces very large kittens and resemble the wild parent geoffrey's cat alot. The geoffrey's cat is completely missing f series of chromosomes (which are some of the more pronounced chromosomes in the domestic cat species so I have read) and also has an extra c chromosome i believe. Would this make the cat larger than normal or cause any fertility problems in females (with other cross there have been fertile females produced and when mated with domestics have gone to produce f2 cats with varying numbers of chromosomes) also what the effect be on meiosis in the embryos with this combo? With mother having the lower number of chromosomes what would be the effect on the embryos? In reality I just want know wether these will be large cats and wether the females will have chance at fertility. I would also like to know if selecting cats that only have 36 chromsomes in the f2 and later generations would produce a more wilder looking cat or have any other effect on personality ect, as I do not know what genetic information is carried on these chromosomes.


    Thanks

    Jesse


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  3. #2  
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    Is this some sort of school project or something you're doing on your own? Assuming you're "successful", is there a possibility that you will create genetic anomalies that won't survive or may survive with handicaps?


    Last edited by PumaMan; September 24th, 2011 at 09:38 PM.
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  4. #3  
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    Quote Originally Posted by macmanmatty View Post
    Thanks

    Jesse
    Can't help you on this one, Jessie!
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  5. #4  
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    This is our own breeding project to try and create f1 safari cats. Very few of these cats have actually been created and those that have are normal cats but also much larger and more intelligent than either cat , but they were created by breeding a MALE geoffrey's cat to a female domestic and I am breeding a FEMALE geoffrey's cat to a male domestic. I basically wonder what the differences would be in this cross and would also like to learn A little more about what we doing here rather than just mating 2 cats together and seeing what happens I would like to know why it happens. Also these f1 cats were used in a study of feline leukemia some that can be found here An X chromosome gene regulates hematopoietic stem cell kinetics
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  6. #5  
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    I'd be interested in seeing how your kitties come out. My daughter has Bengals and after years of living with them says her next cat will be a domestic. Personality problems and health issues mostly. The idea of a larger domestic cat interests me too but I think I would start from the domestic cat base and just select for larger size. Why waste the 5000 years of selective breeding that has already been done to make a human compatible cat?
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