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Thread: Animal Models - question

  1. #1 Animal Models - question 
    Forum Freshman
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    I was talking with a cousin about animal models (he does work involving rat's brains), and asphyxiation. He was talking about CO2 (for asphyxiation high concentrations of CO2 are used) causes a lot of problems in brains (I forget what it does exactly, something about turning on parts of the brain that are not normally on, turning other parts off). It also creates carbonic acid. I asked about nitrogen, and if that would cause problems too - as it would not form an acid - he said he did not know. Does anyone know anything about this?


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  3. #2  
    Veracity Vigilante inow's Avatar
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    Gases tend to be slow and painful, yes. Much better to use cervical dislocation which is quick and much more humane (when performed properly).


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  4. #3  
    Forum Professor Zwirko's Avatar
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    Have a look at the wikipedia article on "Nitrogen asphyxiation" - it should supply you with the relevant information. In short, it's already used in some areas and is even responsible for several accidental deaths a year. Apparently it has even been proposed as a method of execution. There is also some info on the physiology of the process.
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  5. #4  
    Forum Cosmic Wizard i_feel_tiredsleepy's Avatar
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    As far as I know the current ethical guidelines in Canada only allow CO2 asphyxiation and cervical dislocation by hand or with a blade. You have to do a lot of paperwork to get approved to kill an animal any other way.
    "I almost went to bed
    without remembering
    the four white violets
    I put in the button-hole
    of your green sweater

    and how i kissed you then
    and you kissed me
    shy as though I'd
    never been your lover "
    - Leonard Cohen
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  6. #5  
    Time Lord
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    Would anybody care to say offhand the pros & cons of atmospheric N vs. CO2, as (insect) pesticide. Greenhouses and grain elevators.
    A pong by any other name is still a pong. -williampinn
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