Notices
Results 1 to 5 of 5

Thread: Trying to determine the effect of drugs on dehydration

  1. #1 Trying to determine the effect of drugs on dehydration 
    New Member
    Join Date
    Oct 2010
    Posts
    3
    Hello everybody I'm new to this forum and the first thing I'd like to do is a little research of my own. As you can see in the title I'm trying to relate drug usage with dehydration. Here I'll try to explain what I'm trying to do and ask some questions I still have. Feel free to correct me, help me or give me any advice you can give! Its much appreciated!

    Goal: Trying to determine the exact weight of water lost during one night (8 hours) of sleep when using X amount of Y medicine.

    I'm planning on testing the following three medicines/drugs: Alcohol, caffeîne and methylphenidate (which is Ritalin, a medicine I use to control my ADD and which makes me wanna drink/pee all day long).

    Materials: Can't use much since I'll be doing this at home and have no laboratium. All I can pretty much use is a normal inaccurate weighing scale (goes per 0.1 kg) and a more accurate weigh scale that take weigh up to 1500 grams, measuring per gram. Hopefully I can find myself a real nice weighing scale which can weigh up to 80 kgs very precisely per 10 grams or something.

    Method: Everyday I eat and drink the exact same thing, a healthy normale diet without any added salts or other foods that dehydrate. I'll try to pee the same number of times each day and not do any sporting/sweaty stuff. Then I'll pee and weigh myself right before sleep, go to sleep, wake up, pee again and then weigh myself or/and the pee if I can't find a accurate weighing scale(sounds very dirty, but can't find another good method). The weight lost is then the amount of water I lost during the night. Im gonna use this day as my comparison day. Then I'll do the exact same thing, but RIGHT before sleeping I'll take a X amount of my medicines. Then I'll measure myself again when I wake up like I said before and see what the difference is again. Hopefully I can then see the amount of extra water lost because of the medicines! If I can't use a proper weiging scale I'll way the pee and compare that, so I can compare the extra water I pee'd. Which isn't really accurate btw, because then I won't take sweating during night into account. But I'll see.

    Any advice anyone can give me? Things I should pay attention to?

    Thanks


    Reply With Quote  
     

  2.  
     

  3. #2  
    Forum Bachelors Degree
    Join Date
    Aug 2010
    Location
    UK
    Posts
    482
    What a strange experiment.

    May i ask why you wish to conduct this experiment and what you expect to happen?


    The mark of a moderate man is freedom from his own ideas - Tao Te Ching

    Fancy a game of chess?
    http://www.itsyourturn.com/
    Challenge me, Delphi, and join the Pythian games.
    Reply With Quote  
     

  4. #3  
    New Member
    Join Date
    Oct 2010
    Posts
    3
    I'm in my final high school year in Holland, and one of our assignments to pass exams is to conduct a research yourself and write an article about it. It can be anything related to Biology. There are many things that are easier, but I rather try and research something that can't be found on the internet and is interesting to me. The reason I find it interesting is because ever since I use my medicines, I have this very annoying side effect that I constantly have a dry mouth and a thirsty feeling. This made me interested in to why this was actually happening, which is why I took this as my subject.

    I expect to prove if the medicines make my body dehydrate and how much water will be lost extra because of this medicine. Hopefully I get some clear results that show 20mg (my usual 3 hour dosis) of Ritalin make my body lose X more water than normal.
    Reply With Quote  
     

  5. #4  
    Forum Bachelors Degree
    Join Date
    Aug 2010
    Location
    UK
    Posts
    482
    Interesting, you have picked a difficult one. There's lots of scope there though.

    If you want to see what affect Ritalin is having on you, why are you also including an alcohol arm and a caffeine arm? And during the alcohol and caffeine arms are you planning to continue taking Ritalin or stop?

    These are some ethical issues you need to address - but addressing them is part of the experiment. Read up a little on Declaration of Helsinki, which explains why ethics are so important to such experiments.


    Drinking alcohol as part of a high school experiment? I thought you Dutch were liberal, but not that liberal!
    And don't stop taking your medications!
    The mark of a moderate man is freedom from his own ideas - Tao Te Ching

    Fancy a game of chess?
    http://www.itsyourturn.com/
    Challenge me, Delphi, and join the Pythian games.
    Reply With Quote  
     

  6. #5  
    New Member
    Join Date
    Oct 2010
    Posts
    3
    Interesting response, thanks! You asked me why I chose to include caffeîne and alcohol into my experiments. It was because I felt testing one certain medicine wasn't really that interesting for the teacher to read. She doesn't take Ritalin and that might make it a more interesting read for her if I would include caffeîne and alcohol (which she might be in contact with daily, caffeîne ofcourse) Indeed I didn't really take a close look wether it's a smart idea to include alcohol in my research. Not necessarily because I think it's unhealthy (even though I know it's way more damaging than most people think), but because school might frown upon my decision to include alcohol. I just thought of including it because here in Holland it's actually quite normal to drink regularly from the age of 16 (legal age to buy weak alcohol).

    And yes indeed, I'll be quitting Ritalin during the testing days (except when testing Ritalin ofcourse). Ritalin isn't a crucial medicine. I can live perfectly fine without it. (I usually don't take it in the weekends because of annoying side effects. I only use it during schooldays to improve my concentration) It doesn't cure my ADD, it only hides the symptoms. Combining alcohol or other semi-drugs like caffeîne could be a bad thing, because the dehydration effects add up and with alot of alcohol, caffeine and ritalin it could end in high blood pressure, dehydration and other unwanted things.

    I think I'll just focus on the Ritalin and just use multiple test days so I can get a accurate average result. Do you have any comments on the method I wish to use? Did I leave out important factors?
    Reply With Quote  
     

Bookmarks
Bookmarks
Posting Permissions
  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •