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Thread: CR (calorie restriction) mimetics...how do they work?

  1. #1 CR (calorie restriction) mimetics...how do they work? 
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    I've read that rapamycin is used to mimick calorie restriction..but how?


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  3. #2  
    Forum Professor Zwirko's Avatar
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    Never heard of it myself.

    But google tells me that rapamycin binds to a protein kinase in the TOR signaling pathway (TOR = Target of Rapamycin). Some people think that caloric restriction works by somehow decreasing the activity of this enzyme (which is involved in cell growth, protein synthesis etc).


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