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Thread: NOBEL!! for telomere copy protection.

  1. #1 NOBEL!! for telomere copy protection. 
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    Google it if you want.
    Heres a quote:
    "The long, thread-like DNA molecules that carry our genes are packed into chromosomes, the telomeres being the caps on their ends. Elizabeth Blackburn and Jack Szostak discovered that a unique DNA sequence in the telomeres protects the chromosomes from degradation. Carol Greider and Elizabeth Blackburn identified telomerase, the enzyme that makes telomere DNA. These discoveries explained how the ends of the chromosomes are protected by the telomeres and that they are built by telomerase.
    If the telomeres are shortened, cells age. Conversely, if telomerase activity is high, telomere length is maintained, and cellular senescence is delayed. This is the case in cancer cells, which can be considered to have eternal life. Certain inherited diseases, in contrast, are characterized by a defective telomerase, resulting in damaged cells. The award of the Nobel Prize recognizes the discovery of a fundamental mechanism in the cell, a discovery that has stimulated the development of new therapeutic strategies"

    But shouldn't this mean that we can be immortal somehow?


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  3. #2  
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    No.


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  4. #3  
    Forum Cosmic Wizard spuriousmonkey's Avatar
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    it means we could cover you in cancer.
    "Kill them all and let God sort them out."

    - Arnaud Amalric

    http://spuriousforums.com/index.php
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  5. #4 Re: NOBEL!! for telomere copy protection. 
    Moderator Moderator TheBiologista's Avatar
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    Quote Originally Posted by deigeorge
    Google it if you want.
    Heres a quote:
    "The long, thread-like DNA molecules that carry our genes are packed into chromosomes, the telomeres being the caps on their ends. Elizabeth Blackburn and Jack Szostak discovered that a unique DNA sequence in the telomeres protects the chromosomes from degradation. Carol Greider and Elizabeth Blackburn identified telomerase, the enzyme that makes telomere DNA. These discoveries explained how the ends of the chromosomes are protected by the telomeres and that they are built by telomerase.
    If the telomeres are shortened, cells age. Conversely, if telomerase activity is high, telomere length is maintained, and cellular senescence is delayed. This is the case in cancer cells, which can be considered to have eternal life. Certain inherited diseases, in contrast, are characterized by a defective telomerase, resulting in damaged cells. The award of the Nobel Prize recognizes the discovery of a fundamental mechanism in the cell, a discovery that has stimulated the development of new therapeutic strategies"

    But shouldn't this mean that we can be immortal somehow?
    This is not new research you know. Nobel prizes are a big deal and they don't get awarded to some cutting edge piece of work that came out a few years ago. Those can go either way. Make history or be rather embarrassingly forgotten. You really don't want to be the committee who awarded a Nobel prize for some fashionable piece of research that then gets widely refuted a year later.

    This stuff for example, dates back to 1977. It's really significant, really important. But it's not some miracle breakthrough that's going to turn the world upside down tomorrow. It's a piece of the puzzle, albeit a big piece.
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  6. #5  
    Forum Cosmic Wizard i_feel_tiredsleepy's Avatar
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    One of the 3 who got the nobel for this was a fellow McGill alum

    I was reading up on him and apparently he entered the university at 15, quite the brilliant man.
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  7. #6  
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    i know its a "no" at this point.I also knew the existance of telomere and such researches, the thing is that i thought the specific discovery would be found after decades and i was surprised that it was one of these days.

    I mean,they actually found a way dividing a cell without aging(...not including infamous cancer cells)...that breaks the myth bout immortality in a way and opens the gates to follow the path of real eternal life even if will be only for the few and strong.
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  8. #7  
    Forum Radioactive Isotope skeptic's Avatar
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    While telomere shortening appears to be one of the causes of ageing, it is probably not the only one. There are many suggested mechanisms. While it may be possible, one day, to counter all ageing mechanisms and create a person who does not age, it is not going to happen for a long time, simply because the whole process looks like it is really, really complicated.

    Note that even this is not immortality. However, our privileged descendents may live a very long time before the inevitable catches up with them.
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  9. #8  
    Moderator Moderator TheBiologista's Avatar
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    Quote Originally Posted by deigeorge
    i know its a "no" at this point.I also knew the existance of telomere and such researches, the thing is that i thought the specific discovery would be found after decades and i was surprised that it was one of these days.

    I mean,they actually found a way dividing a cell without aging(...not including infamous cancer cells)...that breaks the myth bout immortality in a way and opens the gates to follow the path of real eternal life even if will be only for the few and strong.
    Dividing a cell without telomere shortening is not the same thing as dividing without ageing. Making cells immortal is also a trivial task. Making people immortal is not at all comparable.
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  10. #9  
    Forum Cosmic Wizard spuriousmonkey's Avatar
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    We all have potentially immortal cells in our body: the germline.

    They have a perfect record. From the first cell ever till now. Unfortunately the new generation of germline cells will be mainly failures. But a few might continue the immortal line.

    that is until the sun goes supernova or something else catastrophic happens to earth.
    "Kill them all and let God sort them out."

    - Arnaud Amalric

    http://spuriousforums.com/index.php
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