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Thread: Equipment for genetic tests

  1. #1 Equipment for genetic tests 
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    Could somebody tell,where is it possible
    to purchase equipment for genetic tests
    and how much does it cost?


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  3. #2  
    Moderator Moderator TheBiologista's Avatar
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    What sort of genetic tests? TBH, if you have to ask on an internet forum, you almost certainly can't afford it, don't have the training to do it or both.

    To do PCR, you need a thermocycler which will cost in the range of 5,000-10,000. You'll need a spectrophotometer to validate your samples, which will cost in the ballpark of 3000. You'll need a microcentrifuge, which will cost at least 1,000. To visualise your samples, you'll need a gel rig, though I'm not sure what those cost. You'll also need micro pipettes, which cost a few hundred euros per set.

    If you're generating biological waste, you'll need to sterilise it using an autoclave which is going to set you back more thousands. Then on top of all of that you'll need to purchase consumables; nuclease-free plastic tubes and pipette tips, a whole host of solvents and powders and of course the PCR reagents themselves. So you're talking money in the range of 10's of thousands of euros or dollars. And that's assuming you have the facilities in place to accommodate this equipment properly.

    The companies involved typically work through local suppliers. Go to the manufacturer websites and they'll usually list the relevant supplier for your area.


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  4. #3  
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    Let's say I wish to open company
    which will do medical genetic tests
    for people.Did I understand you right
    that minimal price for equipment is
    10.000 Euro? What if I purchase
    used equipment?I'm not geneticist
    myself so I will need to hire specialists.
    Could you discribe more in detail what function
    is doing any piece of equipment that you've
    mentioned?
    I'm not going to do any genetic engineering
    for now,only tests.
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  5. #4  
    Forum Cosmic Wizard paralith's Avatar
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    As someone who has also worked in a genetics lab, I can verify that every Biologista has described to you is necessary for genetic testing, except for possibly the autoclave - but if you didn't have one of your own you'd have to send your waste to a company which can dispose of it properly and that will still cost you money. And that's is most certainly NOT including everything you would need even to do the most basic of genetic modification in bacteria. In fact, depending on exactly what kind of tests you plan on doing, you may even need a gene sequencer. Some sequence differences can be difficult to detect by PCR alone. I don't know off the top of my head exactly how much a sequencer costs but they are VERY expensive.

    Getting used machines is a bad idea. Accuracy and precision are very important, especially if you want to be testing people, and old machines that nobody wants anymore (which would make them cheap) are that way because they are no longer reliable. Because these things are so expensive people don't get rid of them if they still work sufficiently.

    Edit: Since you have admitted to not being knowledgeable about genetics, I can only assume that your ideas about genetics labs come from popular media like the news, movies, and TV shows. What comes to mind for me are the CSI tv shows where they put tissue in a tube, but the tube in a centrifuge and *ding!* one minute later have the results. That is extremely inaccurate. The process they are imitating for TV takes a lot more equipment than that and takes 3 to 4 hours at the very least.
    Man can will nothing unless he has first understood that he must count on no one but himself; that he is alone, abandoned on earth in the midst of his infinite responsibilities, without help, with no other aim than the one he sets himself, with no other destiny than the one he forges for himself on this earth.
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  6. #5  
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    Do you know if there is possibility to rent equipment needed for genetic tests?
    For example on weekend or at nights or so?
    Do you know if there is some access to such type of equipment or lab for people who are interesting in genetics?
    If you worked in lab maybe you could tell me
    how easy to obtain software for genes analyzing for example to define some inherited disorders?How easy is to define
    parents?
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  7. #6  
    Forum Cosmic Wizard paralith's Avatar
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    Stanley, I doubt there is a renting service. These machines are big and heavy and expensive. I think the best you could do in your situation is find a lab already set up to run these tests and pay them to do it for you. And yes, it is expensive, but there's a reason for that, which you're discovering in this thread. Unless you have oodles of cash to spend on equipment and employees, it's not really reasonable for a layman to just open up a lab or a testing service of their own.
    Man can will nothing unless he has first understood that he must count on no one but himself; that he is alone, abandoned on earth in the midst of his infinite responsibilities, without help, with no other aim than the one he sets himself, with no other destiny than the one he forges for himself on this earth.
    ~Jean-Paul Sartre
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  8. #7  
    Moderator Moderator TheBiologista's Avatar
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    Quote Originally Posted by Stanley514
    Do you know if there is possibility to rent equipment needed for genetic tests?
    For example on weekend or at nights or so?
    Do you know if there is some access to such type of equipment or lab for people who are interesting in genetics?
    If you worked in lab maybe you could tell me
    how easy to obtain software for genes analyzing for example to define some inherited disorders?How easy is to define
    parents?
    None of this stuff is trivial. I really can't see why you'd want to set up such a company without any expertise under your belt. Labs are unlikely to want any part of such a business for legal and insurance reasons. That you have no science training would be a major deterrent too. I really would not recommend used equipment. Most of the equipment will require maintenance and outside of warranty that will be very expensive. Some equipment may require calibration too, which will again add expense. Centrifuges in particular can be dangerous if not regularly inspected, serviced and de-rated as need be.
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